Evidence map›Paper›PMID 40218333›Full record

ArticleAnimals : an open access journal from MDPI2025

Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis.

Slawomir Gonkowski, Manolis Tzatzarakis, Nariste Kadyralieva, Elena Vakonaki, Thomas Lamprakis, Ismail Sen, Askarbek Tulobaev, Fatih R Istanbullugil, Aidai Zhunushova, Liliana Rytel

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Evaluation of Cat Exposure to Bisphenol A (BPA) Using Hair Sample Analysis.Animals : an open access journal from MDPI · 2026
    Article
  2. Bisphenols and follicle function in farm species.The Journal of reproduction and development · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Slawomir GonkowskiDepartment of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-957 Olsztyn, Poland.ORCID 0000-0002-3528-3958
Manolis TzatzarakisLaboratory of Toxicology, School of Medicine, University of Crete, 70013 Heraklion, Greece.
Nariste KadyralievaDepartment of Histology and Embryology, Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, Kyrgyzstan.
Elena VakonakiLaboratory of Toxicology, School of Medicine, University of Crete, 70013 Heraklion, Greece.
Thomas LamprakisLaboratory of Toxicology, School of Medicine, University of Crete, 70013 Heraklion, Greece.
Ismail SenDepartment of Internal Medicine Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, Kyrgyzstan.
Askarbek TulobaevDepartment of Basic Science, Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, Kyrgyzstan.ORCID 0000-0003-1349-6511
Fatih R IstanbullugilDepartment of Food Hygiene and Technology, Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, Kyrgyzstan.ORCID 0000-0001-9610-2797
Aidai ZhunushovaDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, Kyrgyzstan.ORCID 0000-0002-5331-7648
Liliana RytelDepartment of Internal Diseases with Clinics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-720 Olsztyn, Poland.ORCID 0000-0002-6325-1697

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA) is a plasticizer known to have various adverse effects on humans and animals. Exposure of farm animals to BPA negatively impacts their health and poses a threat to humans who consume products of animal origin. Despite the importance of studying the exposure of farm animals to BPA, the knowledge in this area is quite limited. To date, the assessment of BPA levels in dairy cows using analysis of hair samples has not been performed. The study utilized liquid chromatography-mass spectrometry to analyze hair samples collected from 48 dairy cows in the following regions of Kyrgyzstan: Sokuluk, Alamedin and Ysyk Ata. BPA levels above the limit of detection (LOD = 4.8 pg/mg) were noted in 18.8% of analyzed samples. BPA levels in individual samples ranged from below LOD to 89.1 pg/mg with a median value of 9.3 ± 19.7 pg/mg. The study indicates that dairy cows are exposed to BPA, and hair samples can be used for BPA biomonitoring in farm animals. The present study is the first investigation of BPA levels in cows' hair, which is one of the best matrices to study long-term exposure of living organisms to environmental pollutants. Additionally, this study is the first to analyze BPA in biological samples from Kyrgyzstan.

Indexed as

bisphenol Adairy cowsendocrine disruptorsexposure

Identifiers

PMID40218333
PMCPMC11988172

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.