ReviewDiagnostics (Basel, Switzerland)2025
Hybrid Benign Peripheral Nerve Sheath Tumors: A Comprehensive Literature Review with Emphasis on Their Clinical, Morphological and Genetic Features.
Review in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Contemporary Profile of Hybrid Nerve Sheath Tumors: Clinical, Anatomical, and Imaging Characteristics.Cancers · 2026Article
- Solitary Neurofibroma of the Hypopharynx: A Case Report.Clinical case reports · 2026Article
- Characterizing Pain in Peripheral Nerve Tumors: Interim Results from a Prospective Bicenter Cohort.Cancers · 2026Article
- A Rare Case of Diffuse Extra-Cranial Schwannomatosis of the Trunk and Limbs.Clinical case reports · 2026Article
- A case report of malignant transformation in neurofibromatosis type 1: pain and rapid growth as key indicators for early biopsy.Frontiers in oncology · 2026Article
- Hybrid neurofibroma/schwannoma in schwannomatosis-a diagnostically challenging benign peripheral nerve sheath tumour.Familial cancer · 2025Review
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Authors and funding
10 authors.
Funding
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Abstract
Hybrid Peripheral Nerve Sheath Tumors (HPNSTs) are rare benign neoplasms that exhibit a combination of histological features from multiple types of benign peripheral nerve sheath tumors, including schwannomas, neurofibromas, and perineuriomas. These tumors present a diagnostic challenge due to their morphological and histological variability. In this article, we aim to summarize the key morphological, histological, and molecular characteristics of HPNSTs, providing insights into their diagnostic approaches. We review the different hybrid subtypes, including schwannoma-perineurioma, schwannoma-neurofibroma, and perineurioma-neurofibroma, emphasizing their clinical features, genetic associations, and the role of surgical excision as the gold-standard treatment.
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Registered trials
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