Evidence map›Paper›PMID 40217929›Full record

ArticleJournal of clinical medicine2025

Evaluation of Presepsin for Early Diagnosis of Sepsis in the Emergency Department.

Andrea Piccioni, Silvia Baroni, Gloria Rozzi, Fabio Belvederi, Simone Leggeri, Fabio Spagnuolo, Michela Novelli, Giulia Pignataro, Marcello Candelli, Marcello Covino and 2 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Diagnostic and Prognostic Value of Presepsin in Sepsis: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Is GDF15 a Feasible Biomarker in Sepsis?Diagnostics (Basel, Switzerland) · 2025
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andrea PiccioniDepartment of Emergency Medicine, Fondazione Policlinico Universitario A. Gemelli-IRCCS, 00168 Rome, Italy.ORCID 0000-0001-5703-8737
Silvia BaroniUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0009-0009-8528-7533
Gloria RozziUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.
Fabio BelvederiUnit of Chemistry, Biochemistry and Clinical Molecular Biology, Department of Laboratory and Hematological Sciences, Fondazione Policlinico Universitario Agostino Gemelli-IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0009-0007-2117-3161
Simone LeggeriUnit of Chemistry, Biochemistry and Clinical Molecular Biology, Department of Laboratory and Hematological Sciences, Fondazione Policlinico Universitario Agostino Gemelli-IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0009-0003-0683-2967
Fabio SpagnuoloUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.
Michela NovelliUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.
Giulia PignataroDepartment of Emergency Medicine, Fondazione Policlinico Universitario A. Gemelli-IRCCS, 00168 Rome, Italy.ORCID 0000-0003-3394-3913
Marcello CandelliDepartment of Emergency Medicine, Fondazione Policlinico Universitario A. Gemelli-IRCCS, 00168 Rome, Italy.ORCID 0000-0001-8443-7880
Marcello CovinoDepartment of Emergency Medicine, Fondazione Policlinico Universitario A. Gemelli-IRCCS, 00168 Rome, Italy.ORCID 0000-0002-6709-2531
Antonio GasbarriniUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-6230-1779
Francesco FranceschiDepartment of Emergency Medicine, Fondazione Policlinico Universitario A. Gemelli-IRCCS, 00168 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EDmolecular biomarkerspresepsinscore and sepsissepsis

Identifiers

PMID40217929
PMCPMC11989492

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.