Evidence map›Paper›PMID 40217871›Full record

ReviewJournal of clinical medicine2025

Role of Artificial Intelligence in Thyroid Cancer Diagnosis.

Alessio Cece, Massimo Agresti, Nadia De Falco, Pasquale Sperlongano, Giancarlo Moccia, Pasquale Luongo, Francesco Miele, Alfredo Allaria, Francesco Torelli, Paola Bassi and 7 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Alessio CeceDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0009-0007-0151-8230
Massimo AgrestiDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Nadia De FalcoDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Pasquale SperlonganoDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Giancarlo MocciaDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Pasquale LuongoDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Francesco MieleDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Alfredo AllariaDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Francesco TorelliDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Paola BassiDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Antonella SciarraDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Stefano AveniaDepartment of Medicine and Surgery, University of Perugia, 06126 Perugia, Italy.
Paola Della MonicaDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Federica ColapietraDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0009-0004-5630-3956
Marina Di DomenicoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Ludovico DocimoDepartment of General and Specialistic Surgery, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.
Domenico ParmeggianiDepartment of Integrated Activities in Surgery, Orthopedy and Hepato-Gastroenterology, Universitary Policlinico "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-1926-5562

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The progress of artificial intelligence (AI), particularly its core algorithms-machine learning (ML) and deep learning (DL)-has been significant in the medical field, impacting both scientific research and clinical practice. These algorithms are now capable of analyzing ultrasound images, processing them, and providing outcomes, such as determining the benignity or malignancy of thyroid nodules. This integration into ultrasound machines is referred to as computer-aided diagnosis (CAD). The use of such software extends beyond ultrasound to include cytopathological and molecular assessments, enhancing the estimation of malignancy risk. AI's considerable potential in cancer diagnosis and prevention is evident. This article provides an overview of AI models based on ML and DL algorithms used in thyroid diagnostics. Recent studies demonstrate their effectiveness and diagnostic role in ultrasound, pathology, and molecular fields. Notable advancements include content-based image retrieval (CBIR), enhanced saliency CBIR (SE-CBIR), Restore-Generative Adversarial Networks (GANs), and Vision Transformers (ViTs). These new algorithms show remarkable results, indicating their potential as diagnostic and prognostic tools for thyroid pathology. The future trend points to these AI systems becoming the preferred choice for thyroid diagnostics.

Indexed as

artificial intelligence in thyroid nodule diagnosisdeep learninggenomic sequencingmachine learningradiomicsthyroid cancer

Identifiers

PMID40217871
PMCPMC11989500

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.