Evidence map›Paper›PMID 40217779›Full record

ReviewJournal of clinical medicine2025

Management of Atrial Fibrillation in Elderly Patients: A Whole New Ballgame?

Iris Parrini, Fabiana Lucà, Carmelo Massimiliano Rao, Roberto Ceravolo, Sandro Gelsomino, Carlo Ammendolea, Laura Pezzi, Nadia Ingianni, Donatella Del Sindaco, Adriano Murrone and 10 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Observational
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Iris ParriniDepartment of Cardiology, Mauriziano Hospital, 10128 Turin, Italy.ORCID 0000-0002-0038-9445
Fabiana LucàDepartment of Cardiology, Grande Ospedale Metropolitano (GOM) of Reggio Calabria, Bianchi Melacrino Morelli Hospital, 89129 Reggio Calabria, Italy.ORCID 0000-0002-5369-5382
Carmelo Massimiliano RaoDepartment of Cardiology, Santa Maria degli Ungheresi Hospital, Polistena, 89024 Reggio Calabria, Italy.
Roberto CeravoloDepartment of Cardiology, San Giovanni Paolo II Hospital, 88046 Lamezia Terme, Italy.
Sandro GelsominoCardiovascular Department, Maastricht University, 6229HX Maastricht, The Netherlands.ORCID 0000-0002-7746-989X
Carlo AmmendoleaDepartment of Cardiology, San Martino Hospital, 32100 Belluno, Italy.
Laura PezziDepartment of Cardiology, Ospedale Civile dello Spirito Santo, 65100 Pescara, Italy.ORCID 0000-0002-6797-6214
Nadia IngianniCardiology, ASP Trapani, Marsala District, 91022 Castelvetrano, Italy.
Donatella Del SindacoCardiology Unit, Nuovo Regina Margherita Hospital, 00100 Rome, Italy.
Adriano MurroneCardiology Department, Città di Castello Hospital, 06012 Citta di Castello, Italy.ORCID 0000-0003-3184-1921
Giovanna GeraciCardiology Department, Sant'Antonio Abate Hospital ASP Trapani, 91100 Erice, Italy.ORCID 0000-0003-0092-8717
Claudio BilatoDepartment of Cardiology, Vicenza Ovest Hospital, Arzignano, 36100 Vicenza, Italy.ORCID 0000-0003-3474-0579
Giuseppe ArmentaroDepartment of Internal Medicine and UO of Geriatrics, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-9775-9715
Angela SciacquaDepartment of Internal Medicine and UO of Geriatrics, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-1674-5317
Carmine RiccioCardio-Vascular Department, AORN Sant'Anna e San Sebastiano, 81100 Caserta, Italy.
Furio ColivicchiDepartment of Emergency and Acceptance, Presidio Ospedaliero San Filippo Neri, ASL Roma 1, 00135 Rome, Italy.
Massimo GrimaldiDepartment of Cardiology, F. Miulli Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.ORCID 0000-0002-9347-8884
Fabrizio OlivaDepartment of Cardiology, Niguarda Hospital, 20162 Milano, Italy.
Michele Massimo GuliziaDepartment of Cardiology, Garibaldi Nesima Hospital, 95122 Catania, Italy.
Cardiogeriatrics Working Group, Multi-Specialist and Multi-Integrated Approach in Cardiology Working Group and Epidemiology Working Group of Italian Association of Hospital Cardiologists (ANMCO)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most prevalent sustained supraventricular arrhythmia, particularly in older adults, with its incidence increasing dramatically with age. This condition is a significant contributor to morbidity and mortality, being closely linked to an elevated risk of heart failure, ischemic stroke, systemic thromboembolism, and dementia. The complexities of managing AF in the elderly arise from age-related physiological changes, comorbidities, frailty, and the challenges of polypharmacy. Therapeutic strategies must balance efficacy and safety, tailoring interventions to the individual's health status, life expectancy, and personal preferences. This review explores the latest evidence-based approaches to managing AF in elderly patients, focusing on the nuanced application of rate and rhythm control strategies, anticoagulation, and emerging insights into the relationship between AF and cognitive impairment.

Indexed as

anticoagulationatrial fibrillation (AF)cognitive declineelderly patientsheart failure (HF)rate controlrhythm control

Identifiers

PMID40217779
PMCPMC11989488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.