Evidence map›Paper›PMID 40217615›Full record

ReviewJournal of clinical medicine2025

Tumour-Associated Microangiopathic Haemolytic Anaemia with Thrombocytopenia: A Narrative Review and Case Study.

Vedran Kovacic, Marijana Mikacic, Ivan Jerkovic, Tanja Ilic Begovic, Marina Maras

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vedran KovacicInternal Medicine Department, Division of Internistic Intensive Medicine with Clinical Pharmacology and Toxicology, University Hospital of Split, School of Medicine, University of Split, 21000 Split, Croatia.ORCID 0000-0002-9854-2611
Marijana MikacicInternal Medicine Department, Division of Internistic Intensive Medicine with Clinical Pharmacology and Toxicology, University Hospital of Split, School of Medicine, University of Split, 21000 Split, Croatia.
Ivan JerkovicInternal Medicine Department, Division of Internistic Intensive Medicine with Clinical Pharmacology and Toxicology, University Hospital of Split, School of Medicine, University of Split, 21000 Split, Croatia.ORCID 0000-0002-7921-8218
Tanja Ilic BegovicInternal Medicine Department, Division of Internistic Intensive Medicine with Clinical Pharmacology and Toxicology, University Hospital of Split, School of Medicine, University of Split, 21000 Split, Croatia.
Marina MarasInternal Medicine Department, Division of Internistic Intensive Medicine with Clinical Pharmacology and Toxicology, University Hospital of Split, School of Medicine, University of Split, 21000 Split, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombotic microangiopathy (TMA) is a category of diseases consisting of thrombocytopenia, microangiopathic haemolytic anaemia, and widespread occlusive microvascular thrombosis. We report two cases of a thrombotic microangiopathic syndrome associated with non-invasive mucinous cysts and mucinous adenocarcinoma. TMA was treated in both cases by surgical removal of the tumours. We hypothesise that mucin secretion in the case of non-invasive mucinous cysts and paraneoplastic secretion of antibodies in the case of mucinous adenocarcinomas are the causes of endothelial damage with thrombocytopenia and microangiopathic haemolytic anaemia. Finally, patients with TMA who exhibit unusual clinical characteristics or weak responses to plasma exchange should be examined for an underlying tumour. Tumour treatment is the preferred therapy for tumour-associated TMA.

Indexed as

microangiopathic haemolytic anaemiathrombocytopeniatumour

Identifiers

PMID40217615
PMCPMC11989803

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.