Evidence map›Paper›PMID 40217574›Full record

ArticleJournal of Parkinson's disease2025

Parkinson's disease participant-led research on the impact of deep brain stimulation frequency.

Mark D McAuley, John M Dean, Ethan Heming, Alena A Ionova, Celestina A Onabajo, Madison Solie, Sara A Stephenson, Susan E Boehnke

Abstract readCase ReportsLetter
In one paragraph

Article in Journal of Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mark D McAuleySwinburne University of Technology, Melbourne, Victoria, Australia.ORCID 0009-0009-0034-2442
John M DeanTriad Solutions, Inc, Aurora, CO, USA.ORCID 0000-0002-3187-6764
Ethan HemingQueen's University, Kingston, Ontario, Canada.ORCID 0000-0002-0303-3065
Alena A IonovaQueen's University, Kingston, Ontario, Canada.ORCID 0009-0006-4404-2706
Celestina A OnabajoQueen's University, Kingston, Ontario, Canada.ORCID 0009-0007-9875-9937
Madison SolieNipissing University, North Bay, Ontario, Canada.ORCID 0009-0007-3243-0389
Sara A StephensonQueen's University, Kingston, Ontario, Canada.ORCID 0009-0003-1274-8745
Susan E BoehnkeQueen's University, Kingston, Ontario, Canada.ORCID 0000-0002-0726-6659

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease symptoms, including gait disturbances and speech impairment, substantially impact quality of life. This n-of-1 study examined the effects of deep brain stimulation (DBS) frequency on a 54-year-old man with Parkinson's disease. The participant conceived and led the study, embedding patient insight within the project design and execution. The impacts of three DBS frequencies were assessed using markerless motion capture for gait, voice recording for speech analysis, and Kinarm robotic tasks of upper limb coordination and cognitive assessment. The study found that DBS frequency has a clinically significant impact on multiple symptoms, including gait, rigidity, speech and cognitive-motor ability.

Indexed as

Deep Brain StimulationGait Disorders, NeurologicParkinson DiseaseSpeech DisordersHumansMaleMiddle AgedMuscle Rigiditydeep brain stimulationParkinson's disease

Identifiers

PMID40217574
PMCPMC13347481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.