Evidence map›Paper›PMID 40217497›Full record

ReviewBMC oral health2025

Primary giant mucosa-associated lymphoid tissue lymphoma of the lower lip: a case report and literature review.

Maged Ali Al-Aroomi, Luo Baihua, Jie Chen, Ning Li, Canhua Jiang, Jie Wang

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maged Ali Al-AroomiDepartment of Oral and Maxillofacial Surgery, Center of Stomatology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan province, China.
Luo BaihuaDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Jie ChenDepartment of Oral and Maxillofacial Surgery, Center of Stomatology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan province, China.
Ning LiDepartment of Oral and Maxillofacial Surgery, Center of Stomatology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan province, China.
Canhua JiangDepartment of Oral and Maxillofacial Surgery, Center of Stomatology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan province, China. canhuaj@csu.edu.cn.
Jie WangSchool of Basic Medicine, Central South University, Changsha, 410013, Hunan Province, China. wj0988@csu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral lymphomas are rare and difficult to diagnose, with Mucosa-Associated Lymphoid Tissue (MALT) lymphoma most commonly affecting older adults, particularly women. MALT lymphoma of the lip is exceptionally rare, and its cause is poorly understood. We present a case of primary giant MALT lymphoma of the lower lip, explore its clinicopathological features, and review relevant literature. An 83-year-old woman developed a painless, pea-sized swelling on the right lower lip over three years, which gradually increased in size without discomfort. She had no history of chronic infections or autoimmune diseases, and all investigations were unremarkable. Examination revealed a spherical, indurated mass on the left lower lip, measuring 8 cm, with no regional lymphadenopathy. Histology and immunohistochemistry confirmed extranodal marginal zone B-cell lymphoma of MALT. This case underscores the need to consider lymphoma in the differential diagnosis, even without systemic symptoms. Patients with oral MALT lymphoma often achieve complete remission after treatment, but diagnosing it can be challenging, requiring immunohistochemical testing for confirmation.

Indexed as

Lip NeoplasmsLymphoma, B-Cell, Marginal ZoneAged, 80 and overDiagnosis, DifferentialFemaleHumansLipLymphomaMucosa-associated lymphoid tissue (MALT)Non-Hodgkin lymphomaOral mucosa

Identifiers

PMID40217497
PMCPMC11987177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.