Evidence map›Paper›PMID 40217452›Full record

ArticleBMC ophthalmology2025

Corneal endothelial and retinal microvascular changes in pseudoexfoliation syndrome: insights from specular microscopy and OCT angiography.

Kursat Atalay, Ibrahim Kocak, Nihat Sayin, Busra Cirak

Abstract read
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kursat AtalayKanuni Sultan Suleyman Training and Research Hospital, Eye Clinic, Istanbul, 34303, Atakent Mah. Turgut Ozal Blv. Kucukkcekmece, Turkey. kursat.atalay@saglik.gov.tr.
Ibrahim KocakKanuni Sultan Suleyman Training and Research Hospital, Eye Clinic, Istanbul, 34303, Atakent Mah. Turgut Ozal Blv. Kucukkcekmece, Turkey.
Nihat SayinKanuni Sultan Suleyman Training and Research Hospital, Eye Clinic, Istanbul, 34303, Atakent Mah. Turgut Ozal Blv. Kucukkcekmece, Turkey.
Busra CirakKanuni Sultan Suleyman Training and Research Hospital, Eye Clinic, Istanbul, 34303, Atakent Mah. Turgut Ozal Blv. Kucukkcekmece, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the correlation between corneal specular microscopy (SM) and macular optical coherence tomography angiography (OCTA) data in patients with pseudoexfoliation syndrome (PXS).

methodsThis was a cross-sectional, prospective study. Consecutive patients aged > 45 years with PXS or normal examination results were included. We examined cell density (CD), average cell area (AVG), coefficient of variation (CV), and hexagonality values from the SM. We collected 6 × 6 mm macular OCTA data with a quality score of 6/10 or higher.

resultsThirty-five eyes with PXS and 32 healthy eyes were evaluated. The CD, AVG, CV, and hexagonality for the PXS group were 2388.5 ± 368.8 cell/mm

conclusionHighlighting the observed lack of correlation between SM and macular OCTA findings in PXS patients in this study emphasizes the necessity of prioritizing early detection of anterior segment changes. The results indicate that immediate monitoring and intervention could reduce undesired consequences and maintain visual function in those affected.

Indexed as

Endothelium, CornealExfoliation SyndromeFluorescein AngiographyMicrovesselsRetinal VesselsTomography, Optical CoherenceAgedCell CountCross-Sectional StudiesFemaleHumansMaleMicroscopyMiddle AgedProspective StudiesCornea endotheliumOCTAOptical coherence tomographyPseudoexfoliationSpecular microscope

Identifiers

PMID40217452
PMCPMC11992760

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.