ArticleBMC oral health2025
Quantitative evaluation of parotid gland dysfunction in patients with hyposalivation using magnetic resonance imaging mapping technique : Quantification of Parotid gland function using MRI.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Advanced magnetic resonance imaging techniques for structural and functional assessment of salivary glands.Radiology and oncology · 2026Review
- The Application of Magnetic Resonance Imaging in Dentistry: A Bibliometric Analysis.International dental journal · 2026Review
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Authors and funding
6 authors.
Funding
Abstract
objectiveThis study aimed to assess the feasibility of quantitative magnetic resonance imaging (MRI) employing the multi-dynamic multi-echo (MDME) technique as a diagnostic modality for evaluating glandular dysfunction in patients with hyposalivation.
methodsThe MDME technique generated T1, T2, and proton density (PD) maps of the parotid gland, allowing for the simultaneous acquisition of values from the respective mappings. The Mann-Whitney U-test was used to compare the hyposalivation and control groups, and receiver operating characteristic (ROC) curve analysis was performed.
resultsA total of 71 patients who underwent MDME MRI were reviewed and categorized into hyposalivation patients (n = 32) and healthy controls (n = 25). The average T1, T2 and PD value of the gland in the hyposalivation group were 606.92 ms, 91.85 ms, and 82.52 pu, respectively, whereas those in the control group were 628.08 ms, 80.69 ms, and 91.12 pu, respectively. The T2 and PD values were significantly different between the hyposalivation and control groups. The cut-off T2 value was 85.75 ms (AUC = 0.8131, p < 0.0001) and the cut-off PD value was 81.55 pu (AUC = 0.7588, p = 0.0009).
conclusionsT2 and PD values derived from the MDME technique demonstrated strong potential for detecting parotid gland dysfunction in hyposalivation patients. These findings suggest that MDME-based quantitative MRI mapping shows promise in evaluating hyposalivation of the parotid gland and could become a valuable diagnostic tool in clinical settings.
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Registered trials
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