Evidence map›Paper›PMID 40217388›Full record

ReviewActa epileptologica2024

Research progress on the electrophysiological indicators to predict the efficacy of vagus nerve stimulation for drug-refractory epilepsy.

Guangli Li, Zhenguang Li, Yingting Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Acta epileptologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Guangli LiHunan University of Chinese Medicine, Changsha, 410208, Hunan Province, China.
Zhenguang LiEpilepsy Center of Brain Hospital of Hunan Province, Changsha, 410007, Hunan Province, China. 405291204@qq.com.
Yingting LiuEpilepsy Center of Brain Hospital of Hunan Province, Changsha, 410007, Hunan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vagus nerve stimulation (VNS) is an important treatment option for drug-refractory epilepsy (DRE), with well-established efficacy and safety in clinical practice for more than 20 years. However, it is very difficult to find the optimal electrophysiological indicators for the effectiveness of VNS on DRE because the mechanism of action is unknown. In this review, we provide an update of the potential applications of VNS outcomes in patients with drug-resistant epilepsy. Electroencephalographic (EEG) activity, event-related potentials, EEG synchronization levels, magnetoencephalographic, laryngeal muscle evoked potentials, and heart rate variability are potential biomarkers for VNS outcomes in people with DRE.

Indexed as

Aryngeal muscle evoked potentialDrug-refractory epilepsyEfficacyElectroencephalogramElectrophysiologyEvent-related potentialHeart rate variabilityMagnetoencephalographyPredictive indicatorsVagus nerve stimulation

Identifiers

PMID40217388
PMCPMC11960364

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.