Evidence map›Paper›PMID 40217269›Full record

ArticleBMC research notes2025

Lesionia: a digital data management system to enhance collaborative management of epidemiological and clinical data of cutaneous leishmaniases patients.

Emna Harigua-Souiai, Youssef Ben Salem, Maaoui Hariga, Yusr Saadi, Hejer Souguir, Hamed Chouaieb, Olufemi Adedokun, Imen Mkada, Zeineb Moussa, Akila Fathallah-Mili and 6 more

Abstract read
In one paragraph

Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Emna Harigua-SouiaiLaboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia. harigua.emna@gmail.com.
Youssef Ben Salem *Laboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Maaoui Hariga *Laboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Yusr SaadiLaboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Hejer Souguir *Laboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Hamed Chouaieb *Service de Parasitologie, Faculté de Médecine de Sousse, Hôpital Farhat Hached, Université de Sousse, Sousse, Tunisia.
Olufemi AdedokunUniversity of Ibadan Research Foundation, Ibadan, Nigeria.
Imen MkadaLaboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Zeineb MoussaLaboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Akila Fathallah-MiliLaboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Meryem LemraniLaboratory of Parasitology and Vector-Borne-Diseases, Institut Pasteur du Maroc, Casablanca, Morocco.
Nabil HaddadUniversity of Public Health, Beirut, Lebanon.
Ayoade OduolaUniversity of Ibadan Research Foundation, Ibadan, Nigeria.
Oussama SouiaiLaboratory of Bioinformatics, Mathematics and Statistics LR16IPT09, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Insaf Bel Hadj AliLaboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Ikram GuizaniLaboratory of Molecular Epidemiology and Experimental Pathology - LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.

Funding

National Academies of Sciences, Engineering, and Medicine NAS-USAID PEER program - cycle 5 (PEER518; agreement number No. AID-OAA-A-11-00012)The Initiative of Clinical Investigation Centre (CIC) at Institut Pasteur de Tunis (CIC2016IPT02)The Ministry of Higher Education and Research in Tunisia (LR16IPT04)Wellcome Trust/FCDO, managed by the Science for Africa Foundation SFA del05-22
6 · The paper itself

Abstract

Digital Systems for Data Management (DSDM) have become a critical cornerstone in collaborative biomedical research and clinical trials involving multiple investigators, institutions, and populations. DSDM provide unique features that ensure that data meet the standards of FAIR (Findability, Accessibility, Interoperability and Reusability). We herein present Lesionia, a DSDM designed to support the PEER518 consortium that aimed at developing new cutaneous leishmaniases (CL) diagnostics using samples and data collected from patients suspected of having CL in countries in the MENA region and West Africa. The consortium involved nine institutions across five countries: Tunisia, Morocco, Lebanon, Mali, and the USA, and informally Scientists from Algeria and Nigeria. The guidelines on the data to be collected by the clinicians and biologists during the project were used for the development of a Questionnaire that served as a basis for the implementation of a dedicated web-based DSDM.Lesionia was developed and validated for the management and the analysis of clinical and epidemiological data in the diagnosis of CL. It consists of a relational database, a web-based user interface (WUI) and a tool for experimental data handling and analysis of clinical and epidemiological data of CL cases. The platform was deployed and validated during the PEER518 project using data collected across the involved teams. Lesionia is expandable to include further collaborators, partners, and projects. It is designed for data handling from the consented patient interview and sample collection to the samples' storage and investigation. The WUI permits data entry, fetching, visualization and analysis. Rigorous controls on data entry were implemented to reduce discrepancies. It also offers a set of analysis tools that range from descriptive statistics to variable correlation analysis. Lesionia is accessible in a secure manner to all users of the consortium through a web browser.Lesionia will be a valuable tool for collaborative and integrative management of clinical and epidemiological data. It is an open-source software that can broadly serve the scientific community interested in studying, controlling, reporting, and diagnosing CL and similar cutaneous diseases.

Indexed as

Data ManagementLeishmaniasis, CutaneousHumansUser-Computer InterfaceClinical dataCutaneous leishmaniasesDatabaseDigital data managementEpidemiologyStatistics

Identifiers

PMID40217269
PMCPMC11987383

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.