ArticleBMC oral health2025
3-D changes in tooth position after treatment with mandibular advancement devices -a retrospective study in a non-university setting.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Sensor-derived wearing time predicts 3D orthodontic side effects during mandibular advancement therapy of obstructive sleep apnea.Clinical oral investigations · 2026Article
- Impact of Mandibular Advancement Therapy on Occlusal Plane Orientation and Incisor Inclination in Obstructive Sleep Apnea Patients: A Retrospective Observational Study.Journal of clinical medicine · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile mandibular advancement devices (MADs) are effective in reducing obstructive sleep apnoea (OSA)-related events, they can also cause occlusal changes. Three-dimensional (3D) techniques have rarely been used to evaluate the dental side effects. The aim of this study was to evaluate 3D tooth movement in patients with sleep apnea and to assess the effects of two designs: side wing and side thrust.
methodsVirtual models of dental casts were superimposed at baseline (T0), after 11.9 ± 7.1 months (T1), and 31.9 ± 25.4 months (T2), evaluating 3D tooth movement, overjet, and overbite. Teeth were grouped into anterior (canine to canine) and posterior (bilateral first premolar to second molar) segments. Normality was checked (Shapiro-Wilk). T-tests, ANOVA, and regression analyses assessed differences in tooth movement, overjet/overbite changes, and influencing factors (P <.05).
resultsA total of 58 patients diagnosed with obstructive sleep apnea (mean age: 50.7 ± 12.4 years; 44 males) were included. Observation period 1 (T0 and T1; OP1, n = 58) involved 28 wing (Somnodent flex and fusion) and 30 thrust (IST + and classic, Narval CC, Hamburger UPS) appliances, while observation period 2 (T0 and T2; OP2, n = 21) included 12 and 9, respectively. Over the treatment period, overjet and overbite decreased (p ≤.06), with increased maxillary palatal inclination, distal tooth translation in the anterior/posterior segments, and palatal movement of the anterior segment (p ≤.037). Wing appliances demonstrated greater reductions in overjet and overbite (p ≤.06), maxillary posterior segment extrusion (p =.003), and mesio-buccal translation in mandibular segments (p ≤.023) during OP2. Regression analysis indicated that wing appliances significantly influenced overjet and overbite in OP2 (p ≤.047).
conclusionsMAD therapy resulted in progressive dental changes, including mesio-occlusion and anterior open bite, and appeared to be tilting of the entire row rather than physical movement, with wing appliances showing greater, although clinically insignificant, effects.
trial registrationRegistry: drks.de; Name: Changes in tooth position after treatment with mandibular advancement devices as part of the treatment of sleep-related breathing disorders; URL: https://drks.de/search/en/trial/DRKS00034679 Identifier: DRKS00034679, date of registration: 17. July 2024.
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