ReviewBritish dental journal2025
Symptomatic irreversible pulpitis and other orofacial pain: overcoming challenges in diagnosis and management.
Review in British dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Cannabis-associated hyperalgesia and reduced local anesthetic efficacy in oral surgery: A case report.Toxicology reports · 2026Article
- Neural Mechanisms and Brain Alterations in Orofacial Pain: A Narrative Review of Human Neuroimaging.Diagnostics (Basel, Switzerland) · 2026Review
- Neurobiological Links Between Endodontic Pain and Temporomandibular Disorders: A Comprehensive Review.Cureus · 2026Review
- Dental Cement Placement to Temporize Recalcitrant Dental Pain From Acute Pulpitis.Journal of the American College of Emergency Physicians open · 2026Article
- Follow-Up After Urgent Endodontic Care: A Retrospective Exploratory Study in a University Clinic.Medicina (Kaunas, Lithuania) · 2026Article
- Case Report: Ultrasound-guided dual-target low-temperature plasma ablation for refractory cervicogenic orofacial pain-a report of two cases.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Tooth Pulp Afferents and Transient Receptor Potential (TRP) Ion Channels as Key Regulators of Pulp Homeostasis, Inflammation, and Pain.International journal of molecular sciences · 2025Review
- Decoding orofacial pain: a translational review of mechanisms and novel therapies.The journal of headache and pain · 2025Review
- Changes in galectin-1 expression in pulp tissue and CD68 + macrophages in irreversible pulpitis and healthy pulp.Journal of molecular histology · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the unique sensory innervation of the teeth and face, orofacial pain can be challenging to diagnose and manage. Odontogenic pain, or 'toothache', is the most common orofacial pain condition and encompasses the vast majority of pain which is presented to dental practitioners. While diagnosis is often straightforward, the clinical picture is occasionally unclear or contradictory, and in these situations, the clinician should be able to consider reasons other than the teeth for the patient's presenting complaint. The primary aim of managing odontogenic pain is to treat the underlying cause, often arising from the dental pulp or periapical tissues; however, several factors can make pre-, intra- and post-operative management of odontogenic pain challenging. This paper will consider key similarities and differences in the clinical presentation of odontogenic pain and other non-odontogenic causes of orofacial pain in order to help practitioners arrive at the correct diagnosis. We discuss evidence-based recommendations for intra- and post-operative management of acute odontogenic pain, and consider the underlying neurophysiological features which make orofacial pain challenging to manage.
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