ReviewBritish dental journal2025
Vital pulp therapies in permanent teeth: what, when, where, who, why and how?
Review in British dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy of theracal as pulp capping material in permanent dentition: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Inflammatory Biomarkers in Irreversible Pulpitis and Pulp Necrosis: A Systematic Review and Meta-Analysis.International dental journal · 2026Pooled it
- An innate defense regulator peptide modulates the inflamed pulp microenvironment and promotes pulp repair.Bioactive materials · 2026Article
- Biofabrication and Characterization of Fluorapatite-Coated Poly(lactic-co-glycolic acid) Microscaffolds: Physicochemical Properties and Human Dental Pulp Stem Cell Responses.Journal of functional biomaterials · 2026Article
- A regenerative strategy for vital pulp therapy: Platelet-rich fibrin augments stem cell viability and pluripotency in bioactive cement environments.Biochemistry and biophysics reports · 2026Article
- Review
- Adherence to endodontic treatment protocols in the clinical practice of Lithuanian dentists and endodontists-cross-sectional study.BMC oral health · 2026Article
- From Caries to Periodontal Breakdown: A Biological and Clinical Continuum Linking Cariology, Operative Dentistry, Endodontics, and Periodontology.Dentistry journal · 2026Review
- Dose-dependent effects of Metformin on proliferation and odontogenic differentiation of dental pulp stem cells.BMC oral health · 2026Article
- Article
- Decision-ready evidence for vital pulp therapy: a network meta-analysis of bioactive materials in mature permanent teeth.Frontiers in dental medicine · 2026Review
- Direct Clinical Evidence of Long-term Hard-tissue Repair after Miniature/Tampon Pulpotomy: An Accidental Re-entry Case after Six Years.Iranian endodontic journal · 2026Article
- Modifications of Biodentine and Their Influence on Endodontic Properties: A Scoping Review.International journal of dentistry · 2026Review
- Intraoperative Identification of Vital Radicular Pulp in a Tooth Diagnosed with Pulp Necrosis: Four-Year Outcome of Tampon Pulpotomy.Iranian endodontic journal · 2026Article
- Comparative evaluation of MTA and PRF for direct pulp capping in permanent mandibular molars - A randomized control trial.Bioinformation · 2026Article
- Role of Dystrophic Calcification in Reparative Dentinogenesis After Rat Molar Pulpotomy.International journal of molecular sciences · 2025Article
- The Outcome of Old-School Indirect Pulp Capping over 40 Years: A Practice-Based Retrospective Evaluation.Dentistry journal · 2025Article
- Evaluation of iRoot BP Plus for Pulpotomy in Permanent Anterior Teeth With Complicated Crown Fractures in Pediatric Patients: A Prospective Cohort Study.International journal of dentistry · 2025Article
- Strontium-doped hydroxyapatite microspheres loaded with iloprost promote dentin-pulp complex regeneration.Frontiers in bioengineering and biotechnology · 2025Article
- A comparative study of endodontic treatment versus surgical procedures in managing dental trauma and tooth avulsion.Bioinformation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dentine-pulp complex is a unique organ that provides nourishment to the dentine and supports the tooth's innervation and defence system. Preserving its health is a key aspect of minimally invasive dentistry. Vital pulp therapies (VPTs), as defined by the European Society of Endodontology, are 'treatment strategies aimed at maintaining the health of all or part of the pulp'. These therapies are particularly useful when pulp inflammation, caused by caries or trauma, threatens pulp vitality and may otherwise lead to necrosis and the need for invasive treatment. VPTs offer several advantages, including the retention of the pulp's immunological functions, maintenance of the structural integrity of the tooth, reduced patient pain and simplified treatment protocols. Additionally, these therapies lower the costs and inconvenience associated with more invasive treatments, benefiting both patients and society. A range of protocols and key factors promoting successful outcomes have been described to guide dental practitioners in adopting VPTs where appropriate. Future considerations for pragmatic research and implementation in primary care are essential to create a sustainable use of VPTs, thus promoting better oral health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.