ArticleScientific reports2025
Association between the geriatric nutritional risk index with the risk of frailty and mortality in the elderly population.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Associations between nutritional risk indices and fall history in older adults: a retrospective cross-sectional study.BMC geriatrics · 2026Article
- Article
- The Geriatric Nutritional Risk Index and pulmonary function predict non-esophageal cancer-related mortality after esophagectomy.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- The Impact of Body Mass Index and Nutritional Status on Cardiac Electrophysiological Balance Using ICEB and ICEBc: A Cross-Sectional Approach.Journal of cardiovascular development and disease · 2026Article
- Article
- Comparative prognostic value of nutrition-inflammation indices for 1-year mortality in elderly intensive care unit patients: a retrospective observational study based on MIMIC-IV database.BMC geriatrics · 2026Observational
- Preoperative low Geriatric Nutritional Risk Index increases intensive care unit admission risk in patients undergoing gastrointestinal tumor surgery.Frontiers in nutrition · 2026Article
- Geriatric nutritional risk Index predicts adverse outcomes across cardiovascular-kidney-metabolic syndrome: discovery in NHANES and external validation in CKM stage 4 patients undergoing PCI.Frontiers in cardiovascular medicine · 2026Article
- Evaluating objective nutritional biomarkers for the prediction of sarcopenia in Crohn's disease: development and internal validation of a clinical nomogram.Frontiers in nutrition · 2026Article
- Geriatric nutritional risk index improves risk scoring for mortality after TAVR compared to established scores.Frontiers in cardiovascular medicine · 2026Article
- Prognostic impact of GNRI-IPI score in octogenarians with diffuse large B-Cell lymphoma treated with R-CHOP.Annals of hematology · 2025Article
- Frailty and nutritional inadequacy in older Korean adults: A gender-stratified analysis using National Survey Data.PloS one · 2025Article
- Addressing sarcopenia management in primary care in Türkiye: gaps in the field and training needs of family physicians.Frontiers in public health · 2025Article
- Association of the dietary inflammation index with frailty in middle-aged and older adults: a systematic review and meta-analysis.Frontiers in nutrition · 2025Review
- Tumour necrosis factor-Frontiers in nutrition · 2025Article
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3 authors.
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Abstract
Frailty is a major health concern among older adults. The Geriatric Nutrition Risk Index (GNRI) is an important instrument for evaluating the nutritional condition in older individuals. Despite its relevance, there remains a paucity of research exploring the relationship between GNRI with the risk of frailty and adverse outcomes. This study aims to investigate the relationship between the GNRI and the risk of frailty and mortality in older adults. Three distinct models were developed, and the association between GNRI and frailty prevalence was investigated using multivariable logistic regression. To explore the relationship between GNRI and mortality among frail individuals, Cox regression analysis was applied. Potential non-linear associations were assessed using restricted cubic spline (RCS) analysis. Interaction tests and stratified analyses were performed to further evaluate the consistency of these associations. This study included 6,753 eligible participants from 2003 to 2018, of whom 34.36% were diagnosed with frailty. After adjusting for all potential covariates, an increase of 1 unit in GNRI was associated with a 7% reduction in frailty prevalence (OR 0.93, 95% CI 0.91-0.95, P < 0.0001). Compared to the low GNRI group, individuals in the high GNRI group had a lower likelihood of being frail (OR 0.41, 95% CI 0.30-0.55, P < 0.0001). Among frail individuals, those with a higher GNRI had a lower risk of mortality relative to those with a lower GNRI (cardiovascular mortality: HR: 0.61, 95% CI 0.43-0.86, P = 0.004; all-cause mortality: HR: 0.58, 95% CI 0.45-0.75, P < 0.0001). The associations between GNRI and frailty prevalence, as well as mortality risk, exhibited consistency in most cases (P for interaction > 0.05). A higher GNRI is significantly related to a diminished prevalence of frailty. In frail older adults, a lower GNRI is an independent predictor of enhanced risk of both total and cardiovascular mortality.
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