ArticleScientific reports2025
To evaluate the effects of artificial tears on ocular biological parameters in dry eye and non-dry eye patients.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Modulation of Total Corneal Astigmatism, Corneal Thickness, and Corneal Higher-Order Aberrations Following Tear-Enhancing Drop Instillation: A Retrospective Comparative Study.Ophthalmology and therapy · 2026Article
- Agreement of ocular biometry and evaluation of IOL calculation using a parameter‑hybrid strategy: a comparison of CASIA2, IOL Master 700, and OA2000 in cataract patients.BMC ophthalmology · 2026Article
- A Practical Approach for Optimizing Ocular Surface Status Before Cataract Surgery to Improve Visual Outcomes and Reduce the Risk of Postoperative Dry Eye.Ophthalmology and therapy · 2025Review
- Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Cataract Surgery: A Prospective Double-Masked Randomized Controlled Clinical Trial.Ophthalmology and therapy · 2025Article
- Long-term Outcomes and Mixed Response in Nivolumab Therapy for Head and Neck Cancer.In vivo (Athens, Greece)Article
- The Effect of Hyaluronic Acid-contained Artificial Tear on Refractive Accuracy of Cataract Surgery in Dry Eye Population: A Retrospective Cohort Study.In vivo (Athens, Greece)Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To analyze the changes in ocular biometry readings in patients with dry eye (DE) and non-dry eye (NDE) after instilling artificial tear drop (ATD). A prospective study was conducted on 98 eyes of 98 patients (DE group, n = 54 eyes; NDE group, n = 44 eyes) who underwent ocular biometry with four consecutive measurements using the IOL Master 700. The baseline flat meridian of the anterior corneal surface (K1), steep meridian of the anterior corneal surface (K2), corneal curvature radius(R1, R2), axial length (AL), anterior chamber depth (ACD), central corneal thickness (CCT), white-to-white corneal diameter (WTW), pupil diameter, non-invasive tear break-up time (NITBUT) and tear meniscus height, (TMH) was measured at baseline, 30-s, 2-min, and 5-min intervals after instilling one drop of ATD. Variability in biometry measurements was assessed and compared. The mean age of the NDE group and DE group was 27.09 ± 10.21 years (30 females, 68.18%) and 29.96 ± 12.08 years (38 females, 70.37%), respectively. Following the application of ATD, intergroup comparisons revealed significant changes in K1 at 2 min and 5 min (p = 0.043, p = 0.043, and p = 0.038, respectively), and significant changes in R1 and R2 at 2 min. Intragroup comparisons showed that AL exhibited significant changes at 30 s (p < 0.001), while CCT demonstrated significant alterations across all time points (p < 0.001). Changes in ACD were observed at 30 s and 2 min in the dry eye group, and pupil diameter showed significant changes at 2 min in both the DE and NDE groups. No significant changes were detected in WTW at any point (all p > 0.05). Artificial tears significantly affect the readings of AL and CCT during ocular biometry. It is recommended to wait for at least 5 min after the installation of eye drops before performing ocular biometry measurements.
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