Evidence map›Paper›PMID 40216873›Full record

Trial reportScientific reports2025

Compared motor learning effects of motor cortical and cerebellar repetitive transcranial magnetic stimulation during a serial reaction time task in older adults.

Saeid Khanmohammadi, Fatemeh Ehsani, Rasool Bagheri, Shapour Jaberzadeh

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saeid KhanmohammadiDepartment of Physiotherapy, School of Rehabilitation Sciences, Semnan University of Medical Sciences, Semnan, Iran.
Fatemeh EhsaniNeuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran. fatemehehsani59@yahoo.com.ORCID https://orcid.org/0000-0002-7528-973X
Rasool BagheriNeuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Shapour JaberzadehNon-invasive Brain Stimulation & Neuroplasticity Laboratory, Department of Physiotherapy, Faculty of Medicine, Nursing and Health Science, Monash University, Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repeated transcranial magnetic stimulation (rTMS) is a technique used to enhance motor learning in older adults. Some studies have shown that applying rTMS to the primary motor cortex (M1) and the cerebellum enhances motor learning. This study investigates the effects of M1 rTMS and cerebellar rTMS on motor learning in older adults. Seventy healthy older participants were randomly divided into M1, cerebellar rTMS, and sham rTMS groups. Participants completed the Serial Reaction Time Task (SRTT), while receiving 10 min of 10 Hz rTMS, with the sham group receiving inactive stimulation. Reaction time (RT) and error rate (ER) were recorded before, immediately, and 48 h post-task. RT and ER decreased immediately after the SRTT in all groups (P < 0.001). Both intervention groups showed greater online motor learning than the sham group (P < 0.05). Additionally, both intervention groups exhibited offline motor learning and learning consolidation with more significant changes in the cerebellar-rTMS group during lasting time (P < 0.03), whereas the sham rTMS group could not maintain motor learning (P > 0.05). The findings suggest that both M1 and cerebellar rTMS enhance motor learning in healthy older adults, with cerebellar rTMS being more effective in consolidating motor learning.

Indexed as

CerebellumLearningMotor CortexReaction TimeTranscranial Magnetic StimulationAgedFemaleHumansMaleMiddle AgedAgingCerebellumMotor cortexMotor learningRepetitive transcranial magnetic stimulationrTMS

Identifiers

PMID40216873
PMCPMC11992138

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.