ArticleScientific reports2025
The simulation and experimental validation of a novel noninvasive multi-target electrical stimulation method.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- [Electric-field modeling, simulation, and experimental analysis of multi-target temporal interference transcranial alternating current stimulation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Article
- A Multi-Channel AM-TMAS Driving System Based on Amplitude-Modulated Sine Waves.Bioengineering (Basel, Switzerland) · 2026Article
- Design and Structure of a Non-Coaxial Multi-Focal Composite Fresnel Acoustic Lens for Synergistic Ultrasound Stimulation of Multiple Brain Regions.Sensors (Basel, Switzerland) · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
The brain is a complex system of structure and function. Brain diseases and brain functional abnormalities often involve multiple functionally connected regions, including the deep brain. Studies have shown that multi-target electrical stimulation is more effective than single-target electrical stimulation. However, non-invasive multi-target electromagnetic stimulation, such as multi-target transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) cannot meet the needs of synchronous multi-target accurate electrical stimulation at the deep brain. In this paper, based on the principle of magneto-acoustic coupling and phased array focusing technology, a novel non-invasive multi-target transcranial magneto-acoustic coupling electrical stimulation (multi-target TMAES) method is proposed. A simulation model and experimental system were established. The simulation and experimental results proved that the proposed multi-target TMAES can non-invasively achieve precise focused electrical stimulation of two targets. The average focal point size of each target is 5.1 mm. The location and intensity of the multi-target electrical stimulation can be flexibly changed by adjusting the system parameters according to the actual need. It will provide a new and promising tool for the treatment of brain diseases and the study of neural circuits and brain functional connectivity.
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Registered trials
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