Evidence map›Paper›PMID 40216616›Full record

ArticleArchives of orthopaedic and trauma surgery2025

Perioperative complications and mid-term outcomes in total hip and knee joint arthroplasty among solid organ transplant recipients: lowest reoperation-free survival and patient survivorship in lung transplant recipients.

Dominic Simon, Jennifer Kalil, Maximilian Lerchenberger, Lennart M Schroeder, Horst Balling, Wolfgang Böcker, Boris M Holzapfel, Jörg Arnholdt, Gautier Beckers

Abstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dominic SimonDepartment of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany. Dominic.Simon@med.uni-muenchen.de.ORCID http://orcid.org/0009-0004-9462-366X
Jennifer KalilDepartment of Surgery, Royal Victoria Hospital, Mcgill University Health Center, 1001 Blvd Decarie, Montreal, QC, H4A 3J1, Canada.ORCID http://orcid.org/0000-0001-6304-4690
Maximilian LerchenbergerDepartment of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.ORCID http://orcid.org/0000-0003-0349-6542
Lennart M SchroederDepartment of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.ORCID http://orcid.org/0000-0003-3966-2637
Horst BallingCenter for Spine Surgery, Neckar-Odenwald-Kliniken gGmbH Buchen, Dr.-Konrad-Adenauer-Str. 37, 74722, Buchen, Germany.ORCID http://orcid.org/0000-0001-6750-9213
Wolfgang BöckerDepartment of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.ORCID http://orcid.org/0000-0003-0554-0201
Boris M HolzapfelDepartment of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.ORCID http://orcid.org/0000-0002-3989-2531
Jörg Arnholdt *Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.ORCID http://orcid.org/0009-0002-0379-1293
Gautier Beckers *Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.ORCID http://orcid.org/0000-0001-7519-4995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPerforming total joint replacements (TJR) in patients with solid organ transplantations (SOT) is associated with an increased risk of complications and reoperation. The aim of this study is to report on implant survivorship, patient survivorship, and complication rates for total knee arthroplasty (TKA) and total hip arthroplasty (THA) performed in heart, lung, liver and kidney transplant recipients. MATERIALS AND

methodsForty patients with heart, lung, liver, or kidney transplants who underwent primary THA or TKA between January 1, 2013, and July 31, 2023, were included. Implant survivorship, reoperation-free survivorship, patient survivorship, and complication rates were compared between the subgroups.

resultsAt a mean follow-up of 5.18 years, Implant survivorship and reoperation-free survival for the entire cohort at the last follow-up were 97.5% and 85%, respectively. Kaplan-Meier survival estimates demonstrated 5- and 10-year reoperation-free survival rates of 86.5% (95% CI: 76%-98.4%) and 57.6% (95% CI: 25.6%-100%), respectively. The lung transplant group had the shortest reoperation-free survival, although not statistically significant (p = 0.07), a significantly higher risk of reoperation, with a hazard ratio (HR) of 6.9 (95% CI: 1.1-41.2, p = 0.04) and both the lowest 5-year patient survivorship at 68.6% (p = 0.04) and the highest risk of death after TJR with a HR of 7 (95% CI: 1.2-45.5, p = 0.03).

conclusionPatients with SOT exhibit excellent mid-term implant survivorship, with a rate of 97.5%. Lung transplant recipients show the lowest rates of both reoperation-free survival and overall patient survivorship compared to heart, kidney, and liver transplant recipients. Despite this, the 90-day complication rates are similar across all organ groups.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeOrgan TransplantationPostoperative ComplicationsAdultAgedFemaleHumansLung TransplantationMaleMiddle AgedReoperationRetrospective StudiesComplicationsImplant survivorshipSolid organ transplantationTotal hip arthroplastyTotal knee arthroplasty

Identifiers

PMID40216616
PMCPMC11991998

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.