Evidence map›Paper›PMID 40216606›Full record

ArticleJournal of molecular neuroscience : MN2025

The Role of tRNA Fragments on Neurogenesis Alteration by H₂O₂-induced Oxidative Stress.

Bilge Karacicek, Esra Katkat, Leman Binokay, Gunes Ozhan, Gökhan Karakülah, Sermin Genc

Abstract read
In one paragraph

Article in Journal of molecular neuroscience : MN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bilge KaracicekIzmir Biomedicine and Genome Center, Izmir, Turkey.ORCID http://orcid.org/0000-0003-4834-0146
Esra KatkatIzmir Biomedicine and Genome Center, Izmir, Turkey.ORCID http://orcid.org/0000-0001-7034-9652
Leman BinokayIzmir Biomedicine and Genome Center, Izmir, Turkey.ORCID http://orcid.org/0000-0001-6162-3947
Gunes OzhanIzmir Biomedicine and Genome Center, Izmir, Turkey.ORCID http://orcid.org/0000-0003-1574-9885
Gökhan KarakülahIzmir Biomedicine and Genome Center, Izmir, Turkey.ORCID http://orcid.org/0000-0001-6706-1375
Sermin GencIzmir Biomedicine and Genome Center, Izmir, Turkey. sermin.genc@deu.edu.tr.ORCID http://orcid.org/0000-0001-6126-7460

Funding

Türkiye Bilimsel ve Teknolojik Araştırma Kurumu 118C533
6 · The paper itself

Abstract

Transfer RNAs (tRNAs) are small non-coding RNA molecules transcribed from tRNA genes. tRNAs cleaved into a diverse population tRNA fragments (tRFs) ranging in length from 18 to 40 nucleotides, they interact with RNA binding proteins and influence the stability and translation. Stress is one of the reasons for tRFs cleavage. In our study, we modeled oxidative stress conditions with hydrogen peroxide (H

Indexed as

Hydrogen PeroxideNeurogenesisOxidative StressRNA, TransferAnimalsCell LineEmbryo, NonmammalianMiceMouse Embryonic Stem CellsZebrafishHydrogen PeroxideRNA, TransferH2O2HyPer ZebrafishNSCsTRF-Glu-CTCTRFs

Identifiers

PMID40216606
PMCPMC11991940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.