ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025
Joint Heritability of Sleep EEG Spindle Activity and Thalamic Volume in Early Adolescence.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep spindles, transient bursts of rhythmic activity during non-rapid eye movement sleep, are generated by the thalamocortical network through an intricate interplay between the thalamus and the cortex. Emerging research has shed light on the role of sleep spindles in cognitive function, memory consolidation, and overall brain health. Using a behavioral genetics approach in female and male adolescent humans, this study examined the degree to which sleep spindles (measured via high-density sleep electroencephalography) and thalamic volume (measured via magnetic resonance imaging) are driven by common genetic and environmental factors. Here we show a strong correlation between thalamic volume and sleep spindle amplitude and density. Bayesian structural equation modeling estimated that over posterior regions, genetic factors accounted for approximately half of the covariance between sleep spindle activity and thalamic volume. Our findings demonstrate that genetic factors play a role in shaping the structural and functional integrity of the thalamocortical network, with implications for understanding how these processes contribute to neurodevelopmental outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.