ArticleBMJ health & care informatics2025
Designing an interoperable solution to support pharmacogenomic-guided prescribing in primary care: an implementer report.
Article in BMJ health & care informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesDescribe the implementation of an interoperable solution to support pharmacogenomic-guided prescribing in primary care in the National Health Service, England.
methodsWe used an iterative approach to software development going through clinical workflow mapping, architecture design and development, and pilot-testing.
resultsWe configured a commercial health data management platform to store pharmacogenomic results in a structured format and created a knowledge base of pharmacogenomic guidance. This solution was deployed 'as-a-service' using an open application programming interface (API) specification, allowing third parties to receive pharmacogenomic results and guidance by querying the service using a patient identifier and medicine code. This was integrated with existing clinical decision support tools and presented contextual information to prescribers within their native electronic health record (EHR). DISCUSSION: Pharmacogenomic results and guidance will be used across care settings and have greatest utility at the point of prescribing. This requires a solution, which separates the data from the applications, allowing integration with different EHRs through APIs.
conclusionsA vendor-agnostic standards-based solution can support the implementation of pharmacogenomic-guided prescribing across primary care.
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Registered trials
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