ArticleBMJ open2025
Comparison of non-invasive and fluorescein tear film break-up time in a 65-year-old Norwegian population: a cross-sectional study.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Analytical Performance, Spatial Dynamics and Clinically Meaningful Change Thresholds for Automated Non-invasive Tear Film Assessment Using the Oculus Keratograph 5M.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Dry Eye in Colombian Tomato Farmers: An Exploratory Cross-Sectional Study of Occupational Exposure Duration.Journal of personalized medicine · 2026Article
- Diagnostic Agreement Between Invasive and Non-invasive Assessments for Preoperative Dry Eye Disease Screening in Patients with Cataracts.Ophthalmology and therapy · 2026Article
- The Effect of Tear Film Stability on Variability of Posterior Corneal Curvature Readings with a Swept-Source Optical Biometer in Cataract Patients.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Incomplete rather than complete nasolacrimal duct obstruction Is strongly associated with meibomian gland dysfunction in postmenopausal women with PANDO: a cross-sectional study.Frontiers in medicine · 2026Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMeasurement of tear film stability is central in dry eye disease (DED) diagnosis. In this study, we aimed to compare the performance of two methods of tear film stability measurement: non-invasive tear break-up time (NIBUT) and fluorescein tear film break-up time (FTBUT).
designCross-sectional study. SETTING AND
participantsThe study involved 132 subjects of 65-year-old inhabitants of the Oslo region who were not seeking ophthalmic care.
interventionsThe participants underwent a battery of DED tests, including NIBUT measured on Oculus Keratograph 5M and a traditional method using fluorescein drops (FTBUT). Oculus Keratograph 5M measures two types of NIBUT:; appearance time of the first dry spot (NIBUT
results74 participants (56%) were female and 58 were male (44%). Subjects presented with varying degrees of DED signs and symptoms. Mean values of NIBUT
conclusionNIBUT
Indexed as
Identifiers
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Registered trials
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