Evidence map›Paper›PMID 40215385›Full record

Trial reportThe Journal of clinical psychiatry2025

Combining Ketamine Infusions and Written Exposure Therapy for Chronic PTSD: An Open-Label Trial.

Adriana Feder, Oneysha Brown, Sarah B Rutter, Leah Cahn, Jessica R Overbey, Saren H Seeley, Alex Yu, Philip A Bonanno, Rachel A Fremont, Andrew A Delgado and 8 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of clinical psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Adriana FederDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.
Oneysha BrownDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.
Sarah B RutterDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.
Leah CahnDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.
Jessica R OverbeyDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York.
Saren H SeeleyDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.
Alex YuDepartment of Anesthesiology, Icahn School of Medicine at Mount Sinai, New York, New York.
Philip A BonannoDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
Rachel A FremontDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.
Andrew A DelgadoDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York.
Manish K JhaDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.
Sara CostiDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.
Rachel YehudaDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
Daniela SchillerDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
Robert H PietrzakDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Dennis S CharneyDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.
Denise M SloanDepartment of Psychiatry, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts.
James W MurroughDepartment of Psychiatry, Depression and Anxiety Center for Discovery and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
Training the next generation of clinical neuroscientistsT32MH122394 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rene S. Kahn, ANTONIA S NEW · 2020 to 2026
$2.5M
NCATS NIH HHS UL1 TR004419NIMH NIH HHS T32 MH122394Wellcome Trust
6 · The paper itself

Abstract

Indexed as

Implosive TherapyKetamineStress Disorders, Post-TraumaticAdultChronic DiseaseCombined Modality TherapyFemaleHumansInfusions, IntravenousMaleMiddle AgedTreatment OutcomeKetamine

Identifiers

PMID40215385
PMCPMC12645454

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.