Evidence map›Paper›PMID 40215313›Full record

ArticleScience advances2025

On the role of α-alumina in the origin of life: Surface-driven assembly of amino acids.

Ruiyu Wang, Richard C Remsing, Michael L Klein, Eric Borguet, Vincenzo Carnevale

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruiyu WangDepartment of Chemistry, Temple University, Philadelphia, PA 19122, USA.ORCID 0000-0003-1608-140X
Richard C RemsingDepartment of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA.
Michael L KleinDepartment of Chemistry, Temple University, Philadelphia, PA 19122, USA.ORCID 0000-0002-0027-9262
Eric BorguetDepartment of Chemistry, Temple University, Philadelphia, PA 19122, USA.ORCID 0000-0003-0593-952X
Vincenzo CarnevaleInstitute for Computational Molecular Science, Temple University, Philadelphia, PA 19122, USA.ORCID 0000-0002-1918-8280

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigate the hypothesis that mineral/water interfaces played a crucial catalytic role in peptide formation by promoting the self-assembly of amino acids. Using classical molecular dynamics simulations, we demonstrate that the α-alumina(0001) surface exhibits an affinity of 4

Indexed as

Aluminum OxideAmino AcidsOrigin of LifeDipeptidesGlycineMolecular Dynamics SimulationSurface PropertiesWaterAluminum OxideAmino AcidsDipeptidesGlycineWater

Identifiers

PMID40215313
PMCPMC11988445

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.