Evidence map›Paper›PMID 40215251›Full record

Observational studyPLoS neglected tropical diseases2025

Small but threatening: Punctate Outer Retinal Toxoplasmosis (PORT), a case series report.

Rebeca Paquentín-Jiménez, Ronald Rivera-Sempértegui, Luz Elena Concha-Del-Río

Abstract readCase ReportsObservational Study
In one paragraph

Observational study in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rebeca Paquentín-JiménezInflammatory Eye Disease Clinic, Asociación Para Evitar la Ceguera en México I.A.P, Mexico City, Mexico.
Ronald Rivera-SempérteguiInflammatory Eye Disease Clinic, Asociación Para Evitar la Ceguera en México I.A.P, Mexico City, Mexico.
Luz Elena Concha-Del-RíoInflammatory Eye Disease Clinic, Asociación Para Evitar la Ceguera en México I.A.P, Mexico City, Mexico.ORCID 0000-0002-0081-7745

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo emphasize the importance of promptly assessment of punctate outer retinal toxoplasmosis (PORT), and to present a case series in a third-level reference center in Mexico City.

methodsRetrospective, observational case series of eight eyes of eight patients who presented PORT between January 2020 to February 2023. Diagnosis was made by uveitis specialists based on clinical findings, serology, and multimodal imaging. Descriptive statistics were used to exhibit absolute and relative frequencies.

resultsPatient ages ranged from 19 years to 67 years old. Each patient presented creamy yellowish-white, punctate outer retinal lesions. All patients had SD-OCT showed outer retinal alterations and in autofluorescence presented hyperautofluorescent lesions. 85% of the patients improved their BCVA after treatment, but three (42.8%) were legally blind.

conclusionsPORT is an atypical presentation of ocular toxoplasmosis. Lesions usually lead to retinochoroidal scarring which can significantly diminish a patient's BCVA irreversibly. Recognition of PORT lesions is important since timely and efficacious therapy leads to better visual prognosis and diminish the risk of legal blindness.

Indexed as

Toxoplasmosis, OcularAdultAgedFemaleHumansMaleMexicoMiddle AgedRetinaRetrospective StudiesTomography, Optical CoherenceToxoplasmaYoung Adult

Identifiers

PMID40215251
PMCPMC12058194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.