Evidence map›Paper›PMID 40215236›Full record

ArticlePloS one2025

Prevalence and predictors of long COVID at 1 year in a cohort of hospitalized patients: A multicentric qualitative and quantitative study.

Vignesh Kumar J, Jency Maria Koshy, Divyashree S, Suneetha Narreddy, Mahasampath Gowri S, Priscilla Rupali, Sowmya Sathyendra

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Patient and Professional Perspectives on Long COVID: A Systematic Literature Review and Meta-Synthesis.International journal of environmental research and public health · 2025
    Pooled it
  2. Article
  3. Article
  4. Self-reported Long COVID and its Determinants in a Rural North Indian Adult Population: Lessons Learnt from the Pandemic.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vignesh Kumar JDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.
Jency Maria KoshyDepatment of General Medicine, Believers Church Medical College Hospital, Kerala, India.
Divyashree SInfectious Diseases, MGM New Bombay Hospital, Navi Mumbai, Maharashtra, India.ORCID https://orcid.org/0000-0002-2832-8177
Suneetha NarreddyInfectious Diseases, Apollo Health City, Hyderabad, Telangana, India.
Mahasampath Gowri SDepartment of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.
Priscilla RupaliDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-5115-067X
Sowmya SathyendraDepartment of Medicine-III, Christian Medical College, Vellore, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAccording to WHO long COVID is defined as a continuation or development of new symptoms 3 months after the initial SARS-CoV-2 infection, with these symptoms lasting for at least 2 months with no other explanation. We followed up patients after an episode of acute COVID-19 for 1 year after hospital discharge from different parts of India.

methodsThis was a multi-centric study among patients ≥18 years hospitalized with COVID-19, which recruited patients at 6 weeks after hospital discharge (baseline). Quantitative data on demographics, pre-existing co-morbidities, risk factors, signs and symptoms and hospital parameters during acute COVID-19 infection were noted at baseline. They were followed up and data collected telephonically thereafter at 3-6, 6-9 and 9-12 months regarding self-reported persistence of symptoms. A qualitative component included face to face in-depth interviews to elicit information on perceived health problems, quality of life and financial burden due to COVID-19.

resultsA total of 315 patients were enrolled, with the majority being males (59.4%). The median age was 52 years (IQR 40, 63). The prevalence of long COVID was 16.5%. At 6 weeks and 12 months, 35.2% and 25.9% of patients, reported more than one new symptom that affected their quality of life. Shortness of breath was common at each time point, persistent muscle pain and weakness waxed and waned. Variables at 6 weeks post discharge (baseline) such as shortness of breath (OR 2.22 CI 1.06-4.65, p = <0.05), cough (OR 6.93, CI 2.36-20.30, p = <0.05), fatigue (OR 2.34, CI 1.05-5.23, p = <0.05), and weight loss (OR 2.90, CI 1.30-6.49, p = <0.05) were significantly associated with long COVID.

conclusionWe found that long COVID was noted in 16.5% patients who self reported non - recovery at 1 year. Physical symptoms, mental health issues and mobility were persistent in a significant number of patients following an initial recovery from an acute COVID-19 infection. In 25.9% of patients more than 1 symptom was reported at 1 year after COVID-19. We urgently need therapeutic interventions which can improve the quality of life in these patients.

Indexed as

COVID-19AdultAgedFemaleHospitalizationHumansIndiaMaleMiddle AgedPost-Acute COVID-19 SyndromePrevalenceQuality of LifeRisk FactorsSARS-CoV-2

Identifiers

PMID40215236
PMCPMC11990506

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.