Evidence map›Paper›PMID 40215093›Full record

ReviewInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2025

The impact and management of hyperemesis gravidarum: Current and future perspectives.

L M van der Minnen, I J Grooten, C Dean, J Trovik, R C Painter

Abstract readReview
In one paragraph

Review in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. The impact and management of hyperemesis gravidarum: Current and future perspectives.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

L M van der MinnenAmsterdam Reproduction and Development Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-2485-2174
I J GrootenWilhelmina Kinderziekenhuis, UMC Utrecht, Utrecht, the Netherlands.
C DeanPregnancy Sickness Support, Bodmin, UK.
J TrovikDepartment of Gynaecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
R C PainterAmsterdam Reproduction and Development Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy affecting around 1%-3% of pregnancies worldwide and is the most common reason for hospital admission in early pregnancy. HG can have lasting consequences for both pregnant individuals and their offspring. Current best-practice management includes symptomatic treatment with anti-emetic pharmacological treatment, rehydration if needed, and psychological support. There is a lack of high-quality evidence on treatment for HG. Future research should focus on understanding the cause, developing effective treatment, and so limiting the burden of disease on patients and healthcare systems.

Indexed as

Hyperemesis GravidarumAntiemeticsFemaleFluid TherapyHumansPregnancyAntiemeticshyperemesis gravidarumnausea and vomiting of pregnancypregnancy disorder

Identifiers

PMID40215093
PMCPMC12447674

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.