Evidence map›Paper›PMID 40214970›Full record

ArticleOrthodontics & craniofacial research2025

A Lingual Ultrasound Study of Speech in Patients With Cleft Lip and Palate Following Orthognathic Surgery.

Griffin Lowry, Erika Rezende Silva, Jeannene Matthews, Ayumi Shoji, Timothy Turvey, George Blakey, David Zajac, Jeff Mielke, Laura Anne Jacox

Abstract read
In one paragraph

Article in Orthodontics & craniofacial research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Griffin LowryDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA.
Erika Rezende SilvaDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-9059-1013
Jeannene MatthewsCraniofacial Center, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA.
Ayumi ShojiDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA.
Timothy TurveyDepartment of Oral and Maxillofacial Surgery, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA.
George BlakeyDepartment of Oral and Maxillofacial Surgery, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA.
David ZajacCraniofacial Center, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-9070-7485
Jeff MielkeDepartment of English, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0009-0002-9882-8254
Laura Anne JacoxDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0003-1923-6825

Funding

Orthognathic speech pathology: Understanding how jaw disharmonies and their surgical correction influence speechK08DE030235 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JACOX, LAURA ANNE · 2021 to 2025
$889k
American Association of Orthodontists FoundationNational Science Foundation SMA-1730479NIDCR NIH HHS 1K08DE030235-01A1NIDCR NIH HHS K08 DE030235Oral and Maxillofacial Surgery Foundation
6 · The paper itself

Abstract

objectivesThis study evaluated the effects of orthognathic surgery on speech of Class III ('underbite') patients with repaired cleft lip and palate (CLP) through ultrasound imaging, aerodynamic assessment and articulatory analyses before and after surgery to evaluate how surgery impacts articulation, velopharyngeal (VP) function and hypernasality. MATERIALS AND

methodsTongue gestures of five Class III patients with repaired CLP, five Class III patients without CLP and five Class I controls were visualised through ultrasound imaging pre- and post-surgery. Tongue Dorsum Excursion Index and Tongue Constraint Position Index (TCPI) were calculated using ultrasound, and VP insufficiency (VPI) indices were measured using pressure flow assessment and compared with qualitative-perceptual ratings by Speech-Language Pathologists (SLPs). Linear mixed-effects models were used to test for significant post-operative changes in Dorsum Excursion Index and TCPI among consonants. Pressure flow measures are expected to estimate VP gap size during speech using PERCI-SARS.

resultsPatients with CLP had significantly lower Dorsum Excursion Index for /k/ before front (p = 0.001) and back vowels (p < 0.001). TCPI revealed consistently lower values for patients with CLP than controls and Class III patients, with inter- and intra-speaker variation for all consonants. Pressure flow data of two patients with CLP showed evidence of VPI and altered nasality post-surgery.

conclusionPatients with CLP present with lower Dorsum Excursion Index and TCPI when compared to controls, suggesting more anterior tongue positioning. Dorsum Excursion Index and TCPI can be used to understand tongue shape and movement changes, potentially elucidating functional effects of jaw surgery on speech. Dorsum Excursion Index and pressure flow data indicate increased compensatory articulations and VPI after orthognathic surgery for patients with CLP, impacting speech.

Indexed as

Cleft LipCleft PalateOrthognathic Surgical ProceduresSpeechTongueAdolescentCase-Control StudiesChildFemaleHumansMaleMalocclusion, Angle Class IIISpeech Production MeasurementUltrasonographyVelopharyngeal InsufficiencyYoung Adult

Identifiers

PMID40214970
PMCPMC12355422

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.