Evidence map›Paper›PMID 40214967›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2025

Should animal studies precede human trials for novel myopia control therapies?

Machelle T Pardue, Mingguang He, Lisa A Ostrin

Abstract read
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Machelle T PardueDepartment of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-8738-6839
Mingguang HeState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China.ORCID https://orcid.org/0000-0002-6912-2810
Lisa A OstrinUniversity of Houston College of Optometry, Houston, Texas, USA.ORCID https://orcid.org/0000-0001-8675-1478

Funding

Retinal Mechanisms of Refractive DevelopmentR01EY016435 · NEI · GEORGIA INSTITUTE OF TECHNOLOGY · PI Machelle T. Pardue · 2009 to 2026
$5.4M
VIsion Science Training in AtlantaT32EY007092 · NEI · EMORY UNIVERSITY · PI Machelle T. Pardue · 1985 to 2026
$4.6M
Mechanisms of axial elongation in myopiaR01EY033361 · NEI · GEORGIA INSTITUTE OF TECHNOLOGY · PI C ROSS ETHIER, MAUREEN A KANE · 2022 to 2026
$2.9M
Light, near work, and ocular remodeling and during emmetropization and myopia development in childrenR01EY030193 · NEI · UNIVERSITY OF HOUSTON · PI Lisa A Ostrin, Jason Porter · 2019 to 2026
$2.7M
NEI NIH HHS EY016435NEI NIH HHS EY033361NEI NIH HHS R01 EY016435NEI NIH HHS R01 EY030193NEI NIH HHS R01 EY033361NEI NIH HHS T32 EY007092RRD VA IK6 RX003134U.S. Department of Veterans Affairs RX003134
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40214967
PMCPMC12906869

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.