Evidence map›Paper›PMID 40214945›Full record

ArticleNeuroscience bulletin2025

Transcranial temporal interference stimulation precisely targets deep brain regions to regulate eye movements.

Mo Wang, Sixian Song, Dan Li, Guangchao Zhao, Yu Luo, Yi Tian, Jiajia Zhang, Quanying Liu, Pengfei Wei

Abstract read
In one paragraph

Article in Neuroscience bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mo WangDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, 518055, China.ORCID http://orcid.org/0009-0006-7737-8986
Sixian SongBrain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.ORCID http://orcid.org/0000-0002-7521-6186
Dan LiDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, 518055, China.
Guangchao ZhaoDepartment of Anesthesiology and Perioperative Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Yu LuoShenzhen Zhongkehuayi Technology Co., Ltd, Shenzhen, 518107, China.
Yi TianBrain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Jiajia ZhangBrain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Quanying LiuDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, 518055, China. liuqy@sustech.edu.cn.ORCID http://orcid.org/0000-0002-2501-7656
Pengfei WeiBrain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. pf.wei@siat.ac.cn.ORCID http://orcid.org/0000-0002-1155-6085

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial temporal interference stimulation (tTIS) is a novel non-invasive neuromodulation technique with the potential to precisely target deep brain structures. This study explores the neural and behavioral effects of tTIS on the superior colliculus (SC), a region involved in eye movement control, in mice. Computational modeling revealed that tTIS delivers more focused stimulation to the SC than traditional transcranial alternating current stimulation. In vivo experiments, including Ca

Indexed as

Eye MovementsSuperior ColliculiTranscranial Direct Current StimulationAnimalsMaleMiceMice, Inbred C57BLEye movementFinite element methodSuperior colliculusTemporal interference stimulationTissue phantomTranscranial electrical stimulation

Identifiers

PMID40214945
PMCPMC12314165

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.