Evidence map›Paper›PMID 40214917›Full record

ArticleJapanese journal of radiology2025

Improving early gastric cancer detection in upper gastrointestinal series adding digital tomosynthesis (DTS): a preliminary study.

Masaki Tachi, Koji Sohara, Shinichiro Kumita

Abstract read
In one paragraph

Article in Japanese journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Masaki TachiDepartment of Radiology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-Ku, Tokyo, Japan. m-tachi-555@nms.ac.jp.ORCID http://orcid.org/0000-0003-4858-7907
Koji SoharaDepartment of Radiology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-Ku, Tokyo, Japan.
Shinichiro KumitaDepartment of Radiology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-Ku, Tokyo, Japan.

Funding

Japan Society for the Promotion of Science 20K16837
6 · The paper itself

Abstract

The aim of this study is to evaluate the effectiveness of digital tomosynthesis (DTS) for improving the detection rate of early gastric cancer (EGC) in upper gastrointestinal (UGI) radiography. We retrospectively analyzed 57 patients with 62 pathologically confirmed EGC lesions. Imaging accuracy was compared between conventional double-contrast UGI and UGI with DTS, using endoscopy as the gold standard.In experienced readers, the detection rate improved from 71.0% with conventional radiography to 83.9% with DTS. For less experienced readers, the detection rate significantly increased from 53.4% to 79.0%. For lesions < 2 cm, DTS significantly improved detection only for less experienced readers (p < 0.05). For 2-3 cm lesions, both readers showed significant improvement (p < 0.05 and p < 0.01, respectively). No significant difference was found for lesions ≥ 3 cm. DTS also significantly improved detection for non-ulcerated lesions, particularly those with elevated structures, in the less experienced reader (p < 0.05).AUC analysis showed a slight improvement for experienced readers (0.86 → 0.98, p = 0.0604), while less experienced readers demonstrated significant improvement (0.76 → 0.96, p < 0.01). Inter-reader agreement for conventional radiography was 0.71, which improved to 0.90 with DTS. The total combined radiation dose for UGI and DTS was 4.7-5.3 ± 0.5 mSv, within acceptable limits.UGI with DTS significantly enhances EGC detection, particularly for lesions 2-3 cm and non-ulcerated elevated lesions, improving diagnostic accuracy and consistency, especially for less experienced radiologists. Given its minimal additional examination time (143 s) and cost-effectiveness compared to EGD, DTS may serve as a practical supplementary tool for gastric cancer screening and preoperative evaluation.

Indexed as

Early Detection of CancerRadiographic Image EnhancementStomach NeoplasmsAdultAgedAged, 80 and overContrast MediaFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityContrast MediaDigital tomosynthesisDouble-contrast methodEarly gastric cancerIterative reconstructionUpper gastrointestinal radiographyUpper gastrointestinal series

Identifiers

PMID40214917
PMCPMC12287226

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.