Evidence map›Paper›PMID 40214907›Full record

ArticleJournal of neuro-oncology2025

Epidemiology and palliative care of in-patient cerebral metastases cases in Germany.

Larissa Fink, Christiane von Saß, Heidrun Golla, Raymond Voltz, Felix Muehlensiepen, Christoph J Ploner, Philipp J Slotty, Birgitt van Oorschot, Alexander B Kowski, Marcel A Kamp

Abstract read
In one paragraph

Article in Journal of neuro-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Larissa FinkBrandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Am Seebad 82/83, 15562, Rüdersdorf bei Berlin, Germany.
Christiane von SaßBrandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Am Seebad 82/83, 15562, Rüdersdorf bei Berlin, Germany.
Heidrun GollaDepartment of Palliative Medicine, Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany.
Raymond VoltzDepartment of Palliative Medicine, Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany.
Felix MuehlensiepenCenter for Health Service Research Brandenburg, Brandenburg Medical School Theodor Fontane, Rüdersdorf, Germany.
Christoph J PlonerDepartment of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Philipp J SlottyMedical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.
Birgitt van Oorschot, Rangsdorf, Germany.
Alexander B KowskiDepartment of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Marcel A KampBrandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Am Seebad 82/83, 15562, Rüdersdorf bei Berlin, Germany. marcelalexander.kamp@mhb-fontane.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCerebral metastases (CM) are the most common intracranial neoplasms, significantly impacting patient quality-of-life. Despite advancements in diagnostics and therapeutics, the burden remains high. This study evaluates inpatient management, palliative care use, and mortality outcomes for CM patients in German hospitals in 2022.

methodsA cross-sectional analysis was conducted on 71,787 inpatient cases involving adult CM and leptomeningeal malignancies patients in German hospitals in 2022. Data submitted by hospitals according to §21 of the Hospital Remuneration Act were analyzed, focusing on demographic data, primary tumor types, treatment methods, participation in palliative care, and discharge outcomes.

resultsAmong the 71,787 cases, 53.4% were patients aged 65 years or older. Malignant lung tumors were present in 61.6% of cases, followed by breast malignancies (12%) and malignant melanoma and diffuse diffuse large B-cell lymphoma (each 6.4%). Specialized inpatient palliative care (SIPC) was provided in 14.8% (10,636 cases), with 85.2% not receiving such care. Hospital mortality was 13.1% (9413 cases), with 42.2% of these involving patients who received SIPC. Discharge outcomes included discharge home (72.7%), transfers to other hospitals (7.1%), rehabilitation facilities (0.4%), nursing facilities (2%), and hospices (2.4%).

conclusionDespite treatment advances, high mortality rates for CM patients persist, underscoring the need for palliative care integration and comprehensive training to enhance patient outcomes. Health care planning is a growing topic, our study establishes a benchmark for CM care in German hospitals, revealing a significant number of patients not receiving SIPC. This research can inform future healthcare strategies in neuro-oncology.

Indexed as

Brain NeoplasmsPalliative CareAdultAgedAged, 80 and overCross-Sectional StudiesFemaleGermanyHospital MortalityHumansInpatientsMaleMiddle AgedQuality of LifeYoung AdultAgeCerebral metastasesCerebral neoplasmsEarly integrationMetastatic brain tumorMortalityPalliative care

Identifiers

PMID40214907
PMCPMC12041120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.