Evidence map›Paper›PMID 40214785›Full record

ReviewEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025

ESTES recommendations for the treatment of polytrauma-a European consensus based on the German S3 guidelines for the treatment of patients with severe/multiple injuries.

Cristina Rey Valcarcel, Dan Bieler, Gary A Bass, Christine Gaarder, Frank Hildebrand, ESTES Polytrauma Consensus Group

Registry-linked trialAbstract readReview
In one paragraph

Review in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07208110 (Factors Associated With Mortality by Trauma in the Intensive Care Unit in Villavicencio, Colombia. A Trial Based on a Discharge Registry.), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07208110 recruitingnot on this mapstarted 2026, after this paper: background citation

Factors Associated With Mortality by Trauma in the Intensive Care Unit in Villavicencio, Colombia. A Trial Based on a Discharge Registry.

TypeobservationalSponsorHospital Departamental de VillavicencioRan2026 to 2028Enrolled500ConditionsTrauma (Including Fractures), Trauma ICU Patients, Trauma Injury, Trauma Patients in ICUArmsExposed to trauma, Not exposed
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
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  8. Chinese expert consensus on the prehospital management of major trauma.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026
    Article
  9. Association between sustained moderate hyperglycemia within first 48 hours and poor functional outcome after polytrauma: A retrospective cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Observational
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina Rey ValcarcelUnit of Trauma and Emergency Surgery, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Dan BielerDepartment for Trauma Surgery and Orthopaedics, Reconstructive and Hand Surgery, Burn Medicine, Germany Armed Forces Central Hospital Koblenz, Rübenacher Strasse, 56072, Koblenz, Germany.
Gary A BassDivision of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Christine GaarderDepartment of Traumatology, Oslo University Hospital, Oslo, Norway.
Frank HildebrandDepartment of Orthopaedics, Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Aachen, Germany. fhildebrand@ukaachen.de.
ESTES Polytrauma Consensus Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionConsiderable heterogeneity exists in the configuration and implementation maturity of trauma systems across European healthcare settings, and the opportunities for guideline-informed high-quality care varies considerably. Therefore, the European Society of Trauma and Emergency Surgery (ESTES), with its constituent national societies, has developed comprehensive consensus recommendations for care-context appropriate treatment of polytrauma patients in Europe, from the pre-hospital setting to the first surgical phase.

methodsAdhering to the RAND/UCLA Appropriateness Method (RAM), ESTES conducted a three-round modified Delphi consensus. National society expert delegates assessed Grade of Recommendation (GoR) A and Good Clinical Practice Points (GPP) elements of the German Society of Trauma Surgery (DGU) "S3 guidelines for polytrauma/severe injury management" for appropriateness and implementability within their respective healthcare systems.

resultsIn the first consensus round, 82 GoR A and 57 GPP recommendations were analysed. Of these, seven GPP were rephrased for clarity and four were removed due to redundancy or conflicting content. Consequently, 135 recommendations (82 GoR A and 53 GPP) remained, with 128 (77 GoR A and 51 GPP) deemed appropriate and necessary, and seven as uncertain due to expert disagreement.

conclusionThese ESTES recommendations constitute the first cohesive Europe-wide framework for managing the polytrauma patient from the prehospital setting to the end of the first surgical phase. They serve as a foundational tool for the development of national guidelines, particularly in regions with evolving trauma systems, and promote alignment towards a uniform standard-of-care across Europe.

Indexed as

Multiple TraumaPractice Guidelines as TopicConsensusDelphi TechniqueEuropeGermanyHumansSocieties, MedicalConsensusGuidelinesInjuryPolytraumaRecommendations

Identifiers

PMID40214785
PMCPMC11991986

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.