Observational studyPediatric nephrology (Berlin, Germany)2025
Prevalence of sleep disordered breathing in children with chronic kidney disease.
Observational study in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- The Modular Actigraphy Platform: A Data Science Solution for Processing High-Resolution Time Series Sensor Data for Sleep and Physical Activity Assessment.medRxiv : the preprint server for health sciences · 2025Article
- Etiology and outcomes of primary renal tubular acidosis.Pediatric nephrology (Berlin, Germany) · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundSleep disordered breathing (SDB) is reported in nearly 62% of children with chronic kidney disease (CKD). We report the prevalence and severity of SDB in children with CKD stages 2-5 using polysomnography (PSG).
methodsThis observational, cross-sectional study was conducted in the pediatric nephrology outpatient clinic and sleep medicine laboratory at a tertiary care center in south India from March to December 2023. We enrolled children aged 5-18 years, with CKD stage ≥ 2, including dialysis-dependent and 3 months post-kidney transplantation, and performed the Epworth Sleepiness Scale questionnaire for Children and Adolescents (ESS-CHAD) and PSG after obtaining informed consent. Age-specific values of apnea hypopnea index (AHI) were used to diagnose and measure obstructive sleep apnea (OSA). Comparisons between PSG indices were performed between children with early CKD (stage 2) and advanced CKD (stages 3 to 5 T).
resultsAmong the 36 patients (75% males) with CKD enrolled, even though only 2 (6%) clinically reported SDB as per ESS-CHAD, an overall prevalence of 47% of OSA was observed. Though increasing prevalence and severity was found with increasing stages of CKD, a significant proportion of patients with CKD 2 (50%) had OSA. Moderate to severe OSA was noted only in patients with advanced CKD.
conclusionSDB is prevalent in all stages of CKD in children, with greater severity in higher stages of CKD.
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