Evidence map›Paper›PMID 40214776›Full record

ArticleVirchows Archiv : an international journal of pathology2025

A challenging case of enteric-type lung adenocarcinoma metastatic to the thyroid harboring RET-fusion diagnosed on fine-needle aspiration.

Anna Maria Carillo, Caterina De Luca, Mariantonia Nacchio, Maria Salatiello, Pasquale Pisapia, Vincenzo Damiano, Elena Vigliar, Maria D'Armiento, Giancarlo Troncone, Claudio Bellevicine

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Article in Virchows Archiv : an international journal of pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Anna Maria CarilloDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Caterina De LucaDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Mariantonia NacchioDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Maria SalatielloDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Pasquale PisapiaDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Vincenzo DamianoMedical Oncology, Integrated Activity Department of Onco-Hematological Diseases, Pathological Anatomy and Rheumatic Diseases, AOU Federico II, 80131, Naples, Italy.
Elena VigliarDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Maria D'ArmientoDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Giancarlo TronconeDepartment of Public Health, University of Naples Federico II, Naples, Italy. giancarlo.troncone@unina.it.ORCID http://orcid.org/0000-0003-1630-5805
Claudio BellevicineDepartment of Public Health, University of Naples Federico II, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteric-type lung adenocarcinoma is a histological entity where the enteric component exceeds 50% and must show the expression of at least one immunohistochemical marker of enteric differentiation. The most common differential diagnosis is colorectal carcinoma. Molecular alterations less commonly observed in colorectal adenocarcinoma but more frequently associated with enteric-type lung adenocarcinoma can be helpful in differential diagnosis. In this report, we show a case of a thyroid lesion diagnosed on FNA as a metastasis from colorectal carcinoma and then recognized as a metastasis from enteric-type lung adenocarcinoma thanks to the identification of a RET-fusion through NGS testing. This is the first case of enteric-type lung adenocarcinoma with RET-fusion reported.

Indexed as

AdenocarcinomaAdenocarcinoma of LungBiomarkers, TumorLung NeoplasmsProto-Oncogene Proteins c-retThyroid NeoplasmsBiopsy, Fine-NeedleColorectal NeoplasmsDiagnosis, DifferentialHumansBiomarkers, TumorProto-Oncogene Proteins c-retRET protein, humanEnteric-typeFNALung adenocarcinomaLung cytopathologyRET-fusion

Identifiers

PMID40214776

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.