Evidence map›Paper›PMID 40214743›Full record

ReviewEuropean heart journal2025

Infective endocarditis: it takes a team.

Lawrence Lau, Larry Baddour, Núria Fernández Hidalgo, Thomas D Brothers, William K F Kong, Michael A Borger, Xavier Duval, Christophe Tribouilloy, Jean-Francois Obadia, Mehrdad Golian and 8 more

Abstract readReview
In one paragraph

Review in European heart journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lawrence LauDivision of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, K1Y 4W7 Ottawa, Ontario, Canada.ORCID 0009-0003-0184-4416
Larry BaddourDepartments of Medicine and Cardiovascular Medicine, Division of Public Health, Infectious Diseases and Occupational Medicine, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-4473-7077
Núria Fernández HidalgoServei de Malalties Infeccioses, Hospital Universitari Vall d'Hebron, Barcelona, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Campus Hospitalari, Passeig de la Vall d'Hebron 119-129, 08035 Barcelona, Spain.ORCID 0000-0002-2115-344X
Thomas D BrothersDivision of General Internal Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
William K F KongDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, Singapore.
Michael A BorgerLeipzig Heart Center, University of Leipzig, Leipzig, Germany.
Xavier DuvalUniversité Paris Cité and Université Sorbonne Paris Nord, Inserm 1137, IAME, F-75018 Paris, France.
Christophe TribouilloyDepartment of Cardiology, Amiens University Hospital, Amiens, France.ORCID 0000-0001-7867-3668
Jean-Francois ObadiaChirurgie Cardio-Vasculaire et Transplantation Cardiaque, Hôpital Cardiovasculaire Louis Pradel, 28, Ave. Doyen Lépine, 69677 Bron CEDEX, France.
Mehrdad GolianDivision of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, K1Y 4W7 Ottawa, Ontario, Canada.
Vicente F Corrales-MedinaDivision of Infectious Disease, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.
Francois AuclairDivision of Infectious Disease, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.
Mikael MazighiUniversité Paris Cité, Institut Universitaire de France, Département de Neurologie, Hôpital Lariboisière, et Service de Neuroradiologie Inteventionnelle, Hôpital Fondation Rothschild, FHU NeuroVasc, INSERM UMRS 1144, Paris, France.
Kwan Leung ChanDivision of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, K1Y 4W7 Ottawa, Ontario, Canada.
Bernard PrendergastHeart Vascular and Thoracic Institute, Cleveland Clinic London, London, UK.ORCID 0000-0002-6031-2124
Gilbert HabibAPHM, La Timone Hospital, Cardiology Department, Aix Marseille Université, Marseille, France.
Fraser D RubensDivision of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
David Messika-ZeitounDivision of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, K1Y 4W7 Ottawa, Ontario, Canada.ORCID 0000-0002-6278-5670

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infective endocarditis (IE) is a relatively rare but life-threatening systemic infection, which remains associated with high morbidity and mortality. The epidemiology of IE has shifted to involve an increasing numbers of older patients with both cardiovascular and other types of prosthetic devices, multiple comorbid conditions often requiring invasive procedures, increasingly virulent pathogens, in particular Staphylococcus aureus, or that can harbour anti-microbial resistance, and an escalation of injection drug use in many areas of the world. In parallel, advancements in diagnostic and therapeutic options have led to complex strategies in patients' management. Despite these epidemiologic shifts, clinical trials have been rare and most of the evidence guiding IE management derives from expert consensus or analysis of large registries. Because of this, a multi-disciplinary IE team-based approach has been recommended as the standard of care. The aim of this review is to explore the rationale for a multi-disciplinary team-based approach to the management of IE. This approach has proved to be potentially beneficial based on multiple investigations that have evaluated patient outcomes. In addition, implementation strategies, feasibility and options of the team approach have also been highlighted.

Indexed as

EndocarditisEndocarditis, BacterialPatient Care TeamAnti-Bacterial AgentsHumansStaphylococcal InfectionsAnti-Bacterial AgentsInfective endocarditisMultidisciplinaryTeam

Identifiers

PMID40214743
PMCPMC12193143

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.