Evidence map›Paper›PMID 40214608›Full record

ArticleNanomaterials (Basel, Switzerland)2025

Single-Frame Vignetting Correction for Post-Stitched-Tile Imaging Using VISTAmap.

Anthony A Fung, Ashley H Fung, Zhi Li, Lingyan Shi

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Spatial Glyco-Codes Define Human Liver Pathology and Progression.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anthony A FungDepartment of Biomedical Engineering, Yale University, New Haven, CT 06520, USA.ORCID 0000-0003-1631-7451
Ashley H FungDepartment of Medicine, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0009-0000-6124-666X
Zhi LiShu Chien-Gene Lay Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA.
Lingyan ShiShu Chien-Gene Lay Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-1373-3206

Funding

Novel Optical Imaging Approach to Study Neurovascular Coupling SystemR21NS125395 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHI, LINGYAN · 2022 to 2022
$435k
NINDS NIH HHS R21 NS125395
6 · The paper itself

Abstract

Stimulated Raman Scattering (SRS) nanoscopy imaging offers unprecedented insights into tissue molecular architecture but often requires stitching multiple high-resolution tiles to capture large fields of view. This process is time-consuming and frequently introduces vignetting artifacts-grid-like intensity fluctuations that degrade image quality and hinder downstream quantitative analyses and processing such as super-resolution deconvolution. We present VIgnetted Stitched-Tile Adjustment using Morphological Adaptive Processing (VISTAmap), a simple tool that corrects these shading artifacts directly on the final stitched image. VISTAmap automatically detects the tile grid configuration by analyzing intensity frequency variations and then applies sequential morphological operations to homogenize the image. In contrast to conventional approaches that require increased tile overlap or pre-acquisition background sampling, VISTAmap offers a pragmatic, post-processing solution without the need for separate individual tile images. This work addresses pressing concerns by delivering a robust, efficient strategy for enhancing mosaic image uniformity in modern nanoscopy, where the smallest details make tremendous impacts.

Indexed as

artifact removalimage processingshading correctionSRS nanoscopytile stitchingvignetting

Identifiers

PMID40214608
PMCPMC11990085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.