Evidence map›Paper›PMID 40214487›Full record

ArticleCells2025

Repurposed Drugs to Enhance the Therapeutic Potential of Oligodendrocyte Precursor Cells Derived from Adult Rat Adipose Tissue.

J Pascual-Guerra, M Torres-Rico, B Marín-Rodríguez, M S Arasmou-Idrovo, A G García, J A Rodríguez-Navarro, C L Paíno

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

J Pascual-GuerraServicio de Neurobiología-Investigación, IRYCIS, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0001-6667-3310
M Torres-RicoFundación Teófilo Hernando, 28290 Madrid, Spain.ORCID 0000-0002-5222-2778
B Marín-RodríguezFundación Teófilo Hernando, 28290 Madrid, Spain.
M S Arasmou-IdrovoFundación Teófilo Hernando, 28290 Madrid, Spain.ORCID 0009-0002-3144-5769
A G GarcíaFundación Teófilo Hernando, 28290 Madrid, Spain.
J A Rodríguez-NavarroServicio de Neurobiología-Investigación, IRYCIS, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-0741-6338
C L PaínoServicio de Neurobiología-Investigación, IRYCIS, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0003-4245-592X

Funding

Agencia Laín Entralgo NDG09/014ISCIII CP13-00234, CP19-0010MINECO SAF2013-45570-R, SAF2016-78666RYEI PEJ16/MED/AI-1153, PEJD-2018-PRE/SAL-8532
6 · The paper itself

Abstract

Failure in the proliferation, recruitment, mobilization, and/or differentiation of oligodendrocyte precursor cells (OPCs) impedes remyelination in central nervous system (CNS) demyelinating diseases. Our group has recently achieved the generation of functional oligodendroglia through direct lineage conversion by expressing

Indexed as

Adipose TissueDrug RepositioningOligodendrocyte Precursor CellsAnimalsCell DifferentiationCell MovementOligodendrogliaRatsRats, Sprague-Dawleydrug repurposinglentiviral transductionmyelinoligodendrocytes precursor cells

Identifiers

PMID40214487
PMCPMC11988185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.