Evidence map›Paper›PMID 40214478›Full record

ArticleCells2025

Organoids with a Type 1 Collagen Scaffold to Model Bacterial Cancer Therapy.

Lydia Farrell, Cleo Bonnet, Alethea Tang, Severina Peneva, Non G Williams, Sunil Dolwani, Lee Parry, Paul Dyson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Optimization Strategies and Synergistic Applications of EngineeredInternational journal of nanomedicine · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lydia FarrellInstitute of Life Science, Swansea University Medical School, Singleton Park, Swansea SA2 8PP, UK.ORCID 0000-0002-7643-6009
Cleo BonnetInstitute of Life Science, Swansea University Medical School, Singleton Park, Swansea SA2 8PP, UK.
Alethea TangInstitute of Life Science, Swansea University Medical School, Singleton Park, Swansea SA2 8PP, UK.ORCID 0000-0001-9681-9755
Severina PenevaInstitute of Life Science, Swansea University Medical School, Singleton Park, Swansea SA2 8PP, UK.
Non G WilliamsEuropean Cancer Stem Cell Research Institute, School of Biosciences, Hadyn Ellis Building, Cardiff University, Maindy Road, Cardiff CF24 4HQ, UK.ORCID 0000-0002-1778-3967
Sunil DolwaniSchool of Medicine, Cardiff University, Cardiff and Vale University Health Board, Cardiff CF14 4XN, UK.
Lee ParryEuropean Cancer Stem Cell Research Institute, School of Biosciences, Hadyn Ellis Building, Cardiff University, Maindy Road, Cardiff CF24 4HQ, UK.ORCID 0000-0002-4467-9196
Paul DysonInstitute of Life Science, Swansea University Medical School, Singleton Park, Swansea SA2 8PP, UK.ORCID 0000-0002-0558-2666

Funding

Cancer Research UK C23498/A27517Research Wales Innovation Fund R3-EEF43
6 · The paper itself

Abstract

Bacterial cancer therapy (BCT) is emerging as an important option for the treatment of solid tumours, with promising outcomes in preclinical trials. Further progress is hampered by an incomplete understanding of how oncotropic bacteria, such as attenuated strains of

Indexed as

Collagen Type IModels, BiologicalNeoplasmsOrganoidsTissue ScaffoldsExtracellular MatrixHumansSalmonella typhimuriumCollagen Type Ibacterial cancer therapyorganoidpersonalised medicineSalmonella enterica serovar Typhimuriumtype 1 collagen

Identifiers

PMID40214478
PMCPMC11989105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.