Evidence map›Paper›PMID 40214436›Full record

ArticleCells2025

MIRO1 Is Required for Dynamic Increases in Mitochondria-ER Contact Sites and Mitochondrial ATP During the Cell Cycle.

Benney T Endoni, Olha M Koval, Chantal Allamargot, Tara Kortlever, Lan Qian, Riley J Sadoski, Denise Juhr, Isabella M Grumbach

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benney T EndoniAbboud Cardiovascular Research Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0003-1078-3654
Olha M KovalAbboud Cardiovascular Research Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Chantal AllamargotCentral Microscopy Research Facility, University of Iowa, Iowa City, IA 52242, USA.ORCID 0009-0007-3252-8386
Tara KortleverAbboud Cardiovascular Research Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-0337-4732
Lan QianAbboud Cardiovascular Research Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Riley J SadoskiAbboud Cardiovascular Research Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Denise JuhrAbboud Cardiovascular Research Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0009-0009-8089-7818
Isabella M GrumbachAbboud Cardiovascular Research Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-2285-3157

Funding

Leveraging the mitochondrial regulator MIRO1 to prevent neointimal hyperplasiaR01HL157956 · NHLBI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI GRUMBACH, ISABELLA MARIA, THIEL, WILLIAM H · 2022 to 2025
$2.4M
American Heart Association 17GRNT33660032American Heart Association 22PRE902649BLRD VA I01 BX000163NHLBI NIH HHS R01 HL157956NIH HHS R01 HL 157956
6 · The paper itself

Abstract

Mitochondria-ER contact sites (MERCS) are vital for mitochondrial dynamics, lipid exchange, Ca

Indexed as

Adenosine TriphosphateCell CycleEndoplasmic ReticulumMitochondriaMitochondrial Proteinsrho GTP-Binding ProteinsAnimalsCalciumCell ProliferationFibroblastsMiceMitochondria Associated MembranesAdenosine TriphosphateCalciumMiro-1 protein, mouseMitochondrial Proteinsrho GTP-Binding ProteinsCa2+cell cycleERfibroblastsMAMMERCSMIRO1mitochondriavascular smooth muscle cells

Identifiers

PMID40214436
PMCPMC11988184

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.