Evidence map›Paper›PMID 40214172›Full record

ArticleAmerican journal of hematology2025

The Impact of Melphalan Conditioning and CD34

Eli Muchtar, Vaishali Sanchorawala, Hamza Hassan, Ute Hegenbart, Stefan Schönland, Hans C Lee, Muzaffar Qazilbash, Andrew Kin, Jeffrey Zonder, Eapen Jacob and 12 more

Abstract readMulticenter Study
In one paragraph

Article in American journal of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. [Clinical features and pathological scoring analysis of hepatic amyloidosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Eli MuchtarDivision of Hematology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-2210-2174
Vaishali SanchorawalaSection of Hematology and Oncology, Amyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston Medical Center, Boston, Massachusetts, USA.ORCID 0000-0002-6307-2445
Hamza HassanSection of Hematology and Oncology, Amyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston Medical Center, Boston, Massachusetts, USA.ORCID 0000-0003-1775-2703
Ute HegenbartMedical Department V, Amyloidosis Center, University of Heidelberg, Heidelberg, Germany.ORCID 0000-0003-1917-6746
Stefan SchönlandMedical Department V, Amyloidosis Center, University of Heidelberg, Heidelberg, Germany.
Hans C LeeDepartment of Lymphoma and Myeloma, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0001-8545-3292
Muzaffar QazilbashDepartment of Lymphoma and Myeloma, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-2876-2886
Andrew KinBarbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA.
Jeffrey ZonderBarbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA.
Eapen JacobDivision of Transfusion Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Francis BuadiDivision of Hematology, Mayo Clinic, Rochester, Minnesota, USA.
Angela DispenzieriDivision of Hematology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0001-8780-9512
David DingliDivision of Hematology, Mayo Clinic, Rochester, Minnesota, USA.
Sally AraiStanford University School of Medicine, Stanford, California, USA.
Michelle ChinStanford University School of Medicine, Stanford, California, USA.
Rajshekhar ChakrabortyDivision of Hematology/Oncology, Columbia University Medical Center, New York, New York, USA.ORCID 0000-0001-7336-3003
Suzanne LentzschDivision of Hematology/Oncology, Columbia University Medical Center, New York, New York, USA.
Hila MagenHematology Institute, Chaim Sheba Medical Center, Tel Hashomer, and Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.ORCID 0000-0002-3990-394X
Eden ShkuryHematology Institute, Chaim Sheba Medical Center, Tel Hashomer, and Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.
Caitlin SarubbiDivision of Hematologic Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Heather LandauDivision of Hematologic Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Morie GertzDivision of Hematology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-3853-5196

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Mayo Clinic Transplant Center Scholarly AwardNCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The optimal conditioning schedule and CD34+ cell dose for autologous stem cell transplantation (ASCT) for AL amyloidosis is unknown. Patients (n = 1704) who underwent ASCT for AL amyloidosis between 2003 and 2020 in 9 centers were included. Data on melphalan conditioning dose, number of conditioning days, whether a rest day between conditioning and stem cell infusion was given or not, and infused CD34

Indexed as

Antigens, CD34Hematopoietic Stem Cell TransplantationImmunoglobulin Light-chain AmyloidosisMelphalanTransplantation ConditioningAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTransplantation, AutologousTreatment OutcomeAntigens, CD34MelphalanBMTmarrow/stem cell transplantation‐clinical results in myelomaneoplasia‐myeloma and other plasma cell dyscrasias

Identifiers

PMID40214172
PMCPMC13460254

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.