Evidence map›Paper›PMID 40214101›Full record

ArticleFEBS open bio2025

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca

Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu

Abstract read
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In one paragraph

Article in FEBS open bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Larisa Ioana GogianuDoctoral School of Biology, Faculty of Biology, University of Bucharest, Romania.ORCID https://orcid.org/0000-0001-5361-5680
Lavinia Liliana RutaFaculty of Chemistry, University of Bucharest, Romania.
Claudia Valentina PopaFaculty of Chemistry, University of Bucharest, Romania.
Simona GheneaInstitute of Biochemistry of the Romanian Academy, Bucharest, Romania.
Ileana Cornelia FarcasanuDoctoral School of Biology, Faculty of Biology, University of Bucharest, Romania.ORCID https://orcid.org/0000-0002-4901-7896

Funding

CNFIS-FDI Research, University of Bucharest-2025Credit and Scholarship Agency A.C.B.S of the Romanian Government 118/2023
6 · The paper itself

Abstract

Dimethylsulfoxide (DMSO) is widely used as a solvent or as a carrier when screening for biologic activity of various chemicals, but results need to be interpreted carefully due to its intrinsic toxicity. DMSO has been previously observed to impair the growth of yeast cells defective in calcium movement across cellular membranes and in phosphoinositol pyrophosphate synthases. Here, we set out to investigate the Ca

Indexed as

CalciumDimethyl SulfoxideSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCalcium ChannelsMembrane GlycoproteinsCalciumCalcium ChannelsCCH1 protein, S cerevisiaeDimethyl SulfoxideMembrane GlycoproteinsMID1 protein, S cerevisiaeSaccharomyces cerevisiae Proteinsaequorincalciumdimethylsulfoxideinositol pyrophosphate synthaseSaccharomyces cerevisiae

Identifiers

PMID40214101
PMCPMC12226410

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.