ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Manipulating the Light Systemic Signal HY5 Greatly Improve Fruit Quality in Tomato.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Light regulates capsaicinoid biosynthesis via the CaHY5-CaBBX2-CaACS8 module in pepper.The New phytologist · 2026Article
- Integrated transcriptome-metabolome analyses reveal regulatory networks underlying soluble solids accumulation in Capsicum chinense fruits.The Plant journal : for cell and molecular biology · 2026Article
- Divergent Regulatory Effects of Jasmonic Acid on Tomato Lycopene Biosynthesis Under Light and Dark Conditions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Effects of supplementary lighting with different spectral compositions on plant growth, fruit development, and quality formation of facility-grown tomatoes.Scientific reports · 2026Article
- Regulation of chloroplast biogenesis and differentiation.Journal of experimental botany · 2026Review
- Light regulates tomato fruit metabolome via SlDML2-mediated global DNA demethylation.Journal of integrative plant biology · 2026Article
- Regulatory Mechanisms of Total Soluble Solids in Tomato: From QTL Mapping to Gene Editing.Foods (Basel, Switzerland) · 2025Review
- Review
- Manipulating the Light Systemic Signal HY5 Greatly Improve Fruit Quality in Tomato.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Fruit ripening in tomato fruits comprises dramatic metabolic changes that are regulated by environmental factors. Light not only drives photosynthesis but also acts as a critical signal regulating plant growth, development, and the quality of produce. However, it is unclear how plants sense light signals in the environment to regulate fruit quality. It is demonstrated that the accumulation of Long Hypocotyl 5 (HY5) protein peaks at the breaker stage of fruit maturity, independent of fruit bagging. Genetic manipulation of HY5 reveals that its knockout delays carotenoid synthesis and sucrose conversion, while its overexpression promotes fruit ripening. Molecular and biochemical analyses show that HY5 directly activates the transcript of the key carotenoid synthesis genes, such as Phytoene Synthase 1 (PSY1) and Phytoene Desaturase (PDS), as well as the sucrose metabolism genes, including Lycopersicum Invertase (LIN5, LIN6), Vacuolar Invertase (VI) and Sucrose Synthase (SS1, SS7). Importantly, grafting experiments reveal that HY5 acts as a systemic signal, translocating from leaves to fruits to promote ripening. Furthermore, nightly lighting with red or blue LED greatly improves fruit quality. In summary, the results establish that HY5 as a mobile protein that mediates the systemic light regulation of fruit ripening, offering practical applications for improving fruit quality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.