ArticleCureus2025
131-Radioiodine Therapy for Graves Disease in a Patient With Down Syndrome and Non-operable Congenital Heart Disease.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Thyroid dysfunctions are prevalent in Down syndrome (DS), with hypothyroidism being the most frequent occurrence, whereas hyperthyroidism is rare. DS patients face an increased risk of comorbidities, including gastrointestinal, cardiac, and pulmonary anomalies, as well as developmental delays, endocrine abnormalities, and malignancies, complicating their treatment and management. The published data on pediatric hyperthyroidism in DS from India comprise five case reports with six patients. We report a case of a 13-year-old male child with DS with Graves disease (GD), who had inoperable congenital heart disease (CHD) and was administered iodine-131 radioiodine therapy as a definitive treatment for GD.
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