Evidence map›Paper›PMID 40213709›Full record

ArticleCureus2025

Diagnosis and Endovascular Management of Transplant Renal Artery Stenosis: A Retrospective Two-Decade Study.

Brankica Spasojevic Dimitrijeva, Milan Djukic, Ivana Gojkovic, Srdjan S Nikolovski, Dragan Sagic, Polina Pavicevic, Tijana Radovic, Dragan Vasic, Oliver Radmili, Igor Stefanovic and 2 more

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Brankica Spasojevic DimitrijevaNephrology, University Children's Hospital, Belgrade, SRB.
Milan DjukicCardiology, University Children's Hospital, Belgrade, SRB.
Ivana GojkovicNephrology, University Children's Hospital, Belgrade, SRB.
Srdjan S NikolovskiPathology and Laboratory Medicine, Cardiovascular Research Institute, Loyola University Chicago, Chicago, USA.
Dragan SagicInvasive Diagnostics and Therapy, Institute for Cardiovascular Diseases "Dedinje", Belgrade, SRB.
Polina PavicevicRadiology, University Children's Hospital, Belgrade, SRB.
Tijana RadovicRadiology, University Children's Hospital, Belgrade, SRB.
Dragan VasicClinic for Vascular and Endovascular Surgery, University Clinical Centre of Serbia, Belgrade, SRB.
Oliver RadmiliClinic for Vascular and Endovascular Surgery, University Clinical Centre of Serbia, Belgrade, SRB.
Igor StefanovicCardiology, University Children's Hospital, Belgrade, SRB.
Mirjana KosticNephrology, University Children's Hospital, Belgrade, SRB.
Mirjana CvetkovicNephrology, University Children's Hospital, Belgrade, SRB.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Transplant renal artery stenosis (TRAS) is a potentially treatable posttransplant complication, primarily presenting with arterial hypertension and allograft dysfunction. Its prevalence in children with posttransplant hypertension ranges from 5% to 15%. Diagnosis is typically made through invasive angiography following suspicion raised by echo Doppler findings. Treatment options include medical therapy, percutaneous transluminal angioplasty (PTA)/stenting, and surgical revascularization. This study aimed to assess the efficacy, complications, and outcomes of PTA/stenting procedures in children with TRAS. Methods We reviewed all pediatric patients who underwent renal transplantation in Serbia between June 2001 and February 2023 to identify cases of TRAS treated with PTA. Statistical analysis was performed to compare pre- and post-intervention arterial vessel diameters, serum creatinine levels, estimated glomerular filtration rate (eGFR), mean blood pressure, systolic and diastolic blood pressure indices, and the number of antihypertensive medications used. Results Seven patients underwent PTA with or without stent placement for TRAS. None were treated solely with medical therapy or surgical intervention. The overall prevalence of TRAS was 6.32%, higher in cadaveric transplants (11.11%) compared to living-related transplants (3.39%). Of the seven patients, five underwent PTA alone, while two required stent placement. Two of the five PTA patients required re-interventions, resulting in a total of seven angioplasty procedures. No complications occurred following the procedures. After a mean follow-up of 56.86 ± 45.76 months, patients demonstrated improved blood pressure control and reduced use of antihypertensive medications. While the mean eGFR showed a nonsignificant improvement, one patient with severe concomitant cytomegalovirus disease progressed to grade IV chronic kidney disease. Conclusions PTA, with or without stenting, appears to be an effective and safe treatment for TRAS in children, with immediate and intermediate-term results comparable to those reported in the literature. Stent placement may be particularly suitable for adolescents who have completed their growth phase.

Indexed as

angioplastyblood pressureglomerular filtration ratekidney transplantationrenal artery obstructionstents

Identifiers

PMID40213709
PMCPMC11984333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.