ArticleFrontiers in immunology2025
Knowledge mapping of tumor microenvironment for breast cancer: a bibliometric analysis from 2014 to 2023.
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- COL10A1 overexpression potentially contributes to poor outcomes in breast cancer via autophagy and vasculogenic mimicry.Translational cancer research · 2026Article
- The 3D Collagen Network as a Determinant of Tumor Progression and Drug Delivery Efficiency in Breast Cancer.Pharmaceutics · 2026Review
- The current status and hot topics of endoscopic techniques in breast cancer surgery: a global bibliometric and visualization analysis (1999-2024).Gland surgery · 2026Article
- Bibliometric analysis on the correlation between colorectal cancer and tumor microenvironment [2009-2024].Journal of gastrointestinal oncology · 2025Article
- The landscape of research on B cell and immunotherapy in solid tumors over the past 20 years.Discover oncology · 2025Article
- Emerging trends of the tumor microenvironment in peritoneal malignancies (2010-2024): a visualization analysis.Frontiers in oncology · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Breast cancer is the most common malignant tumor among women worldwide, and the tumor microenvironment (TME) has become a hot research field in contemporary oncology. Understanding the TME is essential for elucidating the mechanisms of breast cancer progression and identifying novel therapeutic targets for metastasis and recurrence. This study performed a bibliometric analysis of TME research for breast cancer, providing a comprehensive overview of current research hotspots, development trends, and directions. Methods: We retrieved for literature on TME for breast cancer published during 2014-2023 from the Web of Science database and performed bibliometric analysis. CiteSpace was used for co-citation analysis of references to assess the evolution and bursts in the knowledge base. VOSviewer was used for co-occurrence analysis of author keywords, countries/regions, institutions, and authors to reveal the knowledge structure and collaborative networks in this research area. Thematic evolution trends were analyzed using the bibliometrix package to reveal research hotspots, thematic evolution and dynamic changes of this research. Results: A total of 9683 documents were included in this study, and the keyword co-occurrence analysis displayed five clusters: immunotherapy, metastasis, diagnosis and prognosis, metabolic regulation, and therapeutic approaches, with the first two keywords, immunotherapy and metastasis, being the most frequently mentioned. The most productive country/region, institution, and author were China (3266 publications), Shanghai Jiao Tong University (208 publications), and Takahashi, Kazuaki (37 publications). Conclusion: In breast cancer TME research, cancer-associated fibroblasts have attracted widespread attention, while cancer immunotherapy has emerged as a key focus in contemporary studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.