ArticleJournal of virus eradication2025
The association between chronic underlying diseases and the clinical characteristics in adult patients infected with Omicron BA.1.
Article in Journal of virus eradication, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The COVID-19 pandemic has been exacerbated by the highly contagious SARS-CoV-2 Omicron variant BA.1, which quickly became the predominant strain worldwide in early 2022. The COVID-19 pandemic has not only burdened healthcare systems but has also led to a new emerging medical question whether chronic underlying diseases (CUDs) are associated with clinical characteristics of populations infected with Omicron BA.1. The purpose of this study is to investigate the impact of CUDs on the clinical characteristics of adult patients (APs) with Omicron BA.1 infection. Methods: We performed an analysis on 320 individuals who were admitted to Tianjin First Central Hospital for treatment in the initial largest outbreak of the Omicron variant BA.1 infection between January and February 2022 in Tianjin, China. Clinical data were collected during the treatment and recovery, including gender, age, vaccination, CUDs, clinical manifestations, and nucleic acid test. These data were statistically analyzed using SPSS software, version 22.0. Results: Our findings suggest that 178 (56 %) out of 320 APs have CUDs at the time of COVID-19 diagnosis. APs with CUDs have a higher median age [55 (40-62)] compared to APs without CUDs [38 (30-47)] and lower vaccination rates [158 (89 %)] compared to APs without CUDs [138 (97 %)]. Multivariable logistic regression results indicate that CUDs and advanced age (≥60 years old) are unfavorable factors for the increase in the severity of Omicron BA.1 infection [age (≥60 years old), OR = 2.96, 95 % CI: 1.35-6.50, Conclusion: This research not only enhances the understanding of the association between CUDs and the clinical manifestations of APs infected with Omicron BA.1, but also offers valuable insights for preventing and managing Omicron BA.1 infections in this demographic. Moreover, it supports the policy of prioritizing vaccination for adults with CUDs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.