Evidence map›Paper›PMID 40213445›Full record

ArticleSmall science2024

Stem-Cell-Based Small-Diameter Blood Vessels with 3D Printing.

Yifan Wang, Xinhuan Wang, Jun Chen, Gordon Wallace, Qi Gu

Abstract read
In one paragraph

Article in Small science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yifan WangKey Laboratory of Organ Regeneration and Reconstruction State Key Laboratory of Membrane Biology Institute of Zoology Beijing 100101 P. R. China.
Xinhuan WangKey Laboratory of Organ Regeneration and Reconstruction State Key Laboratory of Membrane Biology Institute of Zoology Beijing 100101 P. R. China.ORCID https://orcid.org/0000-0001-7751-856X
Jun ChenIntelligent Polymer Research Institute University of Wollongong Innovation Campus, Squires Way North Wollongong NSW 2500 Australia.ORCID https://orcid.org/0000-0003-2218-7382
Gordon WallaceIntelligent Polymer Research Institute University of Wollongong Innovation Campus, Squires Way North Wollongong NSW 2500 Australia.ORCID https://orcid.org/0000-0002-0381-7273
Qi GuKey Laboratory of Organ Regeneration and Reconstruction State Key Laboratory of Membrane Biology Institute of Zoology Beijing 100101 P. R. China.ORCID https://orcid.org/0000-0001-9387-9525

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease has emerged as the leading cause of death worldwide. Since coronary arteries, carotid arteries, and other blood vessels are prone to narrowing, small-diameter artificial blood channels offer a crucial solution for restoring blood flow. Ideal grafts must emulate the structure of natural blood vessels, possess adequate mechanical strength, ensure long-term patency, and incorporate functional cells with minimal immunogenicity. Enhanced cell sources and engineering methods are vital for the creation of functional small-diameter blood vessels (SDBVs). Among potential cell sources, stem cells stand out due to their ability to differentiate into multiple cell types, self-renew, and exhibit low immunogenicity. Additionally, three-dimensionally (3D) printed vascular stents have attracted widespread attention for their precision and controllable bioink application. The need for tissue-engineered blood vessels is currently rising, and innovative design concepts integrating stem cells and 3D printing present promising solutions. Herein, the construction requirements of vascular grafts are reviewed, current status of using stem cells as a cell source and 3D printing as an engineering strategy is described, and prospects and challenges for the development of SDBVs in the medical field are discussed.

Indexed as

3D bioprintingregenerative medicinessmall‐diameter blood vesselsstem cells

Identifiers

PMID40213445
PMCPMC11935029

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.